This version of the course guide is provisional until the period for editing the new course guides ends.

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Integrated Process Design

Code: 43327 ECTS Credits: 6
2025/2026
Degree Type Year
Biological and Environmental Engineering OB 2

Contact

Name:
Javier Garcia Ortega
Email:
xavier.garcia@uab.cat

Teaching groups languages

You can view this information at the end of this document.


Prerequisites

None


Objectives and Contextualisation

To combine chemical, biological and environmental engineering principles, tools and methodologies for the integrated design and intensification of processes, aiming to the design of economically, energetically and environmentally efficient and sustainable processes. 

The learning objectives therefore include identifying and applying criteria (techno economic and environmental) and different approaches to define/select optimal sequences of operations for biotechnological and environmental processes, as well as their integration into biorefineries, with special emphasis in the separation operations and strategies for process intensification.

 

 
 
 
 

Learning Outcomes

  1. CA13 (Competence) Compare the different stages of a process, selecting the sequencing as well the most appropriate alternatives.
  2. CA14 (Competence) Optimise processes energetically from an integrated analysis thereof.
  3. CA14 (Competence) Optimise processes energetically from an integrated analysis thereof.
  4. KA09 (Knowledge) Contrast different separation sequences in the sustainable treatment of waste and in industrial biotechnology processes.
  5. SA13 (Skill) Design continuous-contact separation operations using appropriate mass transfer concepts.
  6. SA14 (Skill) Solve design and operation problems through the analysis of separation operations in biotechnological and environmental processes.
  7. SA15 (Skill) Apply methods, instruments and strategies to develop biotechnological processes and products while observing energy-saving and sustainability criteria.

Content

Unit 1: Introduction. Integrated process design and process intensification concepts. Biorefinery concept.

Unit 2: Bioreactors and operation. Industry 4.0.

Unit 3: Separation operation in biotechnolgical and environmental process engineering. Classification, equipment and use. Calculation methods for design of separation operations.

Unit 4: Integrated design of biotechnological and environmental processes.  Design of biorefineries. Case studies.

Unit 5: Process intensification.  Resources (energy, water, feedstocks) optimisation and waste minimization. Case studies.

 


Activities and Methodology

Title Hours ECTS Learning Outcomes
Type: Directed      
Exercise-based and case study-based teaching 12 0.48
Lectures 27 1.08
Type: Autonomous      
Problem solving and work on case study 32 1.28
Study 62 2.48

Theory classes: Lectures and participation of invited speakers of interest to deliver specific seminars related to the subject.

Class discussion based on proposed readings about key case studies. The case studies introduced by the teaching staff will be worked on in student groups, who will be responsible for explaining and debating the key concepts of the case with the rest of the class.

Development of a group project in which students will select a process case study related to integrated bioprocesses or biorefineries and apply the concepts learned during the course to achieve a more efficient and sustainable production of the target products.

Annotation: Within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.


Assessment

Continous Assessment Activities

Title Weighting Hours ECTS Learning Outcomes
Final exam (individual) 50% 2 0.08 CA13, CA14, KA09, SA13, SA14, SA15
Participation in class and activities 20% 5 0.2 CA13, CA14, KA09, SA13, SA14, SA15
Presentation and discussion case study 10% 2 0.08 SA14, SA15
Written report case study 20% 8 0.32 CA13, CA14, KA09, SA13, SA14, SA15

A) Continuous assessment

The final grade for the course will be based on participation in class debates and activities, completion of a group project and oral presentation, and the final exam.

  • Class participation: 10%

  • Group project monitoring and final report: 20%

  • Oral presentation of the group project: 20%

  • Final exam: 50% – a minimum grade of 4/10 is required in the exam in order to average with the rest of the assessment elements.

B) Reassessment

Students who obtain a grade lower than 4 in the final exam, provided they have achieved an average score above 3 out of 10 in the remaining course activities, may take the resit exam scheduled in the academic calendar.

The reassessment only allows re-evaluation of the final exam component. The other assessment components are not eligible for reassessment.

C) Review of grades

For each assessment activity, a time, date, and location for grade review will be announced, during which the student may review the activity with the teaching staff. In this context, students may submit claims regarding the grade, which will be reviewed by the course instructors. If a student does not attend the scheduled review, the activity will not be reviewed later.

D) Grading

Honours Distinction (Matrícula d’Honor): The award of an Honours Distinction is at the discretion of the teaching staff. According to UAB regulations, MH can only be awarded to students who have achieved a final grade of 9.00 or higher. Up to 5% of enrolled students may receive this distinction.

Students who take the resit exam (partially or entirely) are not eligible for the Honours Distinction.

A student will be considered Not Assessable (NA) if they do not complete a set of activities accounting for at least two-thirds of the total course grade.

E) Irregularities by the student: copying and plagiarism

Without prejudice to other disciplinary measures that may be taken, any irregularities committed by a student that may affect the grade of an assessment activity will result in a grade of zero. This includes cheating, plagiarism, copying, allowing others to copy, etc. Such activities will not be eligible for reassessment. If passing the affected activity is required to pass the course, the course will be failed with no option for recovery during the academic year.

F) Single assessment

This course/module does not allow for a single assessment option.


Bibliography

On-line resources

Integrated Bioprocess Engineering https://app.knovel.com/web/toc.v/cid:kpIBE0002U/viewerType:toc//root_slug:integrated-bioprocess-engineering?kpromoter=marc

Industrial Biotechnology: Products and Processes. https://onlinelibrary.wiley.com/doi/book/10.1002/9783527807833

Continuous Biomanufacturing ‐ Innovative Technologies and Methods. https://onlinelibrary.wiley.com/doi/book/10.1002/9783527699902

Other resources

- Belter PA, Cussler EL, Hu W-S. 1988. Biosepartions. Downstream processing for biotechnology. John Wiley & Sons. ISBN 0-471-84737-2.
 
- Blanch HW, Clark DS. 1996. Biochemical Engineering. Marcel Dekker. ISBN0-8247-8949-0.
 
- Heinzle E, Biwer A, Cooney C. 2006. Development of Sustainable Bioprocesses: Modelling and Assessment. John Wiley & Sons, Ltd.
 
- Harrison RG, Todd PW, Rudge SR, Petrides DP. 2015. Bioseparations Science and Engineering. Oxford University Press. ISBN 978-0-19-539181-7.
 
- Kamm B, Gruber PR, Kamm M (Eds.)  2006. Biorefineries –Industrial Processes and Products. Wiley-VCH Verlag. ISBN 3-527-31027-4.
 
- Marcilla Gomis A. 1999. Introducción a las operaciones de separación de contacto continuo.  Publicacions de la Universitat d'Alacant.
 
- Shuler ML, Kargi F (Eds.) 2002. Bioprocess Engineering. Basic concepts. 2nd Edition. Prentice Hall PTR.  ISBN 0-13-081908-5.
 
- Stuart RT, El-Halwagi MM. 2013. Integrated Biorefineries: Design, Analysis, and Optimization. CRC Press. ISBN 9781439803462.
 
- Ratledge C, Kristiansen B (Eds). 2006. Basic Biotechnology. 3rd Edition. Cambridge University Press.
 
- Recasens Baxarias F. 2018. Procesos deseparación de biotecnología industrial. Publicacions Universitat Politècnica de Catalunya.  Iniciativa Digital Politècnica ebook.
 
-  Shri Ramaswamy; Bandaru V. Ramarao; Hua-Jiang Huang. 2013. Separation and Purification Technologies in Biorefineries. John Wiley & Sons Incorporated. ebook.

Software

No specific software used


Groups and Languages

Please note that this information is provisional until 30 November 2025. You can check it through this link. To consult the language you will need to enter the CODE of the subject.

Name Group Language Semester Turn
(TEm) Theory (master) 1 Catalan first semester afternoon