Degree | Type | Year |
---|---|---|
Nanoscience and Nanotechnology | FB | 1 |
You can view this information at the end of this document.
There are no prerequisites for studying Cell Biology. Nonetheless, in order to ensure the achievement of the learning objetives proposed, it is recommended for the students to have achieved a basic knowledge of biology. It is specially important previous knowledge regarding the general structure of eukaryotic cells, their compartments and their organic molecules such as proteins, nucleic acids, carbohydrates and lipids, as well as basic knowledge of the main pathways of cell metabolism.
On the other hand, in a scientific discipline such as Cell Biology where most bibliography and information resources are in English, it is highly recommended that students have at least a basic knowledge of this language.
Cell Biology is taught in the 1st semester of the 1st year of the degree in Nanoscience and Nanotechnology, and also in the same period in other degrees of the Sciences and Biosciences Faculty. Therefore it can be considered a basic subject. The learning objectives the student should achieve are:
1. Recognize the main differences between prokaryotic and eukaryotic cells.
2. Describe the structure, composition and main characteristics of cell membranes.
3. Explain the organization and composition of other elements of the cell surface.
4. Describe the transport processes through the cell membranes.
5. Describe the structure, composition and function of the different compartments of eukaryotic cells, as well as the relationships between them.
6. Explain the role of mitochondria in cellular bioenergetics.
7. Describe the classification systems and routes of intracellular protein traffic.
8. Describe the composition of chromatin and its organization in interphase and division cells.
9. List the components of the cytoskeleton and describe its composition and structure.
10. Explain the contribution of the cytoskeleton to cell shape and cell movement.
11. Identify and describe the molecules, structures and processes involved in the relationship and communication of the cell with the external environment and with other cells.
12. Identify the molecules involved in the regulation of the cell cycle and explain its function in the cycle control system.
13. List and describe the different phases of the mitotic and meiotic cell division and compare the two types of cell divisions.
14. Relate the functioning of the eukaryotic cell with somediseases.
15. Integrate and apply the theoretical knowledge acquired to interpret the results of simple scientific experiments and to solve simple experimental problems of cell biology.
16. Use the appropriate scientific terminology in the field of cell biology.
CONTENTS OF THE SUBJECT
THEORY LESSONS
Topic 1. Introduction: organization of the prokaryotic and eukaryotic cell. Main characteristics and differences between prokaryotic and eukaryotic cells. Basic techniques for the study of the cell.
Topic 2. Structure, composition and function of the plasma membrane.
Topic 3. Transport of molecules across the membrane. Simple diffusion and osmosis. Transport of ions and small molecules: passive transport by permeases and channel proteins; Primary and secondary active transport.
Topic 4. Nucleus. Structure, functions and bidirectional nucleus-cytoplasm transport. Composition, structure and organization of chromatin in the interphase nucleus.
Topic 5. Cytosol and compartments. Composition and structural organization. Functions of the cytosol.
Topic 6. Endoplasmic reticulum. Structure, composition and functions of the smooth and rough endoplasmic reticulum.
Topic 7. Vesicular transport. Mechanism and types.
Topic 8. Golgi apparatus. Structure, composition and functions of the Golgi apparatus.
Topic 9. Extracellular matrix. Composition and functions. Proteins and polysaccharides. Examples.
Topic 10. Endosomes, lysosomes. Structure, composition and functions.
Item 11. Mitochondria. Structure, composition and functions.
Topic 12. Microtubules. Structure and composition. Tubulin polymerization. Proteins associated with microtubules.
Topic 13. Actin microfilaments. Structure and composition. Polymerization of actin. Actin binding proteins.
Topic 14. Intermediate filaments. Structure and composition. Polymerization. Proteins associated with intermediate filaments.
Topic 15. Junctions and cell adhesion.
Topic 16. Cell signaling. Basic principles of cell signaling.
Topic 17. Cell cycle and mitosis. Phases and control of the cell cycle.
Topic 18. Cell death. Types of cell death. Necrotic and non-necrotic regulated cell death.
Topic 19. Meiosis. Phases of meiosis, chromosome synapse and genetic recombination.
PRACTICAL LESSONS
Practice 1- Introduction to the optic microscope and the plant cell
Practice 2- The animal cell
Practice 3- Introduction to the electronic microscope
Practice 4- Osmosis and simple diffusion
Practice 5- Mitotic cell division
Practice 6- Meiotic cell division
Title | Hours | ECTS | Learning Outcomes |
---|---|---|---|
Type: Directed | |||
Cell biology problems | 4 | 0.16 | |
Practical lessons | 12 | 0.48 | |
Theory lessons | 36 | 1.44 | |
Type: Autonomous | |||
Individual study | 58 | 2.32 | |
Prepare theory topics autonomously | 20 | 0.8 | |
Solving cell biology problems | 10 | 0.4 |
The subject of Cell Biology consists of theoretical lectures, problem classes and practical classes in the laboratory
Theory classes:
The content of the theory program will be taught mainly by the teaching staff in the form of master classes with audiovisual support. The material used in class by the teaching staff will be available on the Virtual Campus of the subject. It is recommended that students visualize it beforehand and use it as a support when taking notes. Although it is not essential to expand the contents of the classes taught by the teaching staff, unless they explicitly request it, it is advisable that students regularly consult the books recommended in the Bibliography section of this teaching guide in order to consolidate and clarify, if necessary, the contents explained in class.
In addition to class attendance, the monitoring of the subject will also involve an active role of the students, who will have to prepare a series of topics of the theory program based on the guidelines provided by the teaching staff. The aim of this activity is to encourage the consultation of bibliographic sources and for students to learn to search, interpret and synthesize information and to work independently. The information collected by the students with the self-study work will serve as individual study material and it will not be necessary to deliver the prepared topics to the teacher. In addition, some of the theoretical classes will be taught in the format of a flipped class. In any of the sessions, the teaching staff will be able to carry out questionnaires to see the evolution in the achievement of the content.
NOTE: 15 minutes of a class will be reserved, within the calendar established by the centre/degree, for students to fill in the surveys for the evaluation of the performance of the teaching staff and the evaluation of the subject.
Lessons of cell biology problems:
There will be 4 problem sessions during the course. The exercises will be related to the contents of the theory program. In the classes, a series of problems or cases of basic cell biology or applied to nanotechnology will be proposed. In addition, any doubts that have arisen from the students during the resolution of the same will be resolved. The resolution of these problems aims for students to consolidate the contents worked on in theory classes (both in the topics taught in person and in the self-study work) and to learn some of the techniques used in cell biology, to become familiar with the interpretation of scientific data and with the resolution of problems based on real experimental situations. In 2 of the problem sessions, a questionnaire will have to be solved with questions of the problems previously worked on. The grade obtained from the questionnaires and the involvement in solving the problems will contribute to the final grade of the subject.
The individual ability of the students to solve a scientific problem will be evaluated in the 2nd midterm exam, where they will have to solve a problem similar to those worked on in the classroom during the semester. The grade obtained from the resolution of this problem will contribute to the final grade of the subject.
Practical lessons:
The practical classes are designed for students to learn to use laboratory instruments, especially the optical microscope, and to complement their theoretical training. A total of 6 practical sessions of 2 hours each will be carried out. Students will work in groups of two people and at the end of each practice they will have to fill out an individual questionnaire about the practice carried out. The practical grade will be the average grade obtained from the resolution of each practical questionnaire, and will contribute to the final grade of the subject.
In order to attend internships, students must prove that they have passed the biosafety and safety tests that they will find on the Virtual Campus and that they are aware of and accept the operating rules of the laboratories of the Faculty of Biosciences.
Annotation: Within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.
Title | Weighting | Hours | ECTS | Learning Outcomes |
---|---|---|---|---|
First partial test (theory lessons) | 35% | 2 | 0.08 | CM08, KM12, KM13, KM14 |
Practical lessons | 20% | 1 | 0.04 | KM14, SM13, SM14 |
Problems solving activity participation | 5% | 4 | 0.16 | CM08, CM09, SM13 |
Second partial test (theory lessons) | 35% | 2 | 0.08 | CM08, KM12, KM13, KM14 |
Solving of a cell biology problem (individually) | 5% | 1 | 0.04 | KM14, SM13 |
EVALUATION
ATTENTION: Attendance at laboratory practices is mandatory. Failure to attend laboratory practices without justification will imply that students can NOT pass the subject.
In order to pass the subject, students must obtain a grade of ≥5 points (out of 10).
1 - CONTINUOUS EVALUATION
1.1 - THEORY:
It will represent 70% of the final grade. There will be 2 partial eliminatory tests of the subject, each of which will have a weight of 35% of the final grade. The first test will be held when approximately half of the theoretical content has been taught. The second test will be carried out once all the theoretical contents have been taught.
Although each midterm exam eliminates material, the second midterm exam will also include, indirectly, content from the first block of topics.
In order for the two partial tests to average, the minimum grade for each of them must be ≥3.5. In addition, the average grade of the 2 midterm tests must be ≥4 in order to pass the subject.
Students who do not take any of the partial tests or who obtain a grade lower than 3.5 in any partial test, or who after taking all the partial tests do not pass the subject, may take the final recovery test and take the corresponding part(s).
Students who have NOT taken the midterm exams without just cause will NOT be able to take the retake exam.
1.2 - PROBLEMS:
It will represent 10% of the final grade and will be obtained from two grades with a weight of 5% each. A 5% will be obtained by solving a problem individually during the 2nd midterm test. Students who do not take the 2nd midterm exam for justified reasons may do this exercise during the final retake exam. The remaining 5% will be obtained from active participation in problem sessions and the resolution of questionnaires at the end of the sessions.
1.3 - PRACTICES IN THE LABORATORY:
Internships represent 20% of the final grade. At the end of each practice, students will make a brief questionnaire about it. The practice grade will be the average obtained from the grades of all the questionnaires.
Failure to attend an internship without justification will result in the reduction of the average grade of the questionnaires to 75%. Failure to attend two practices will imply a reduction of 50%. In case of not attending three or more practices without justification, students will not be able to pass the subject.
In order to attend internships, students must justify having passed the biosafety and safety tests that they will find on the Virtual Campus and be aware of and accept the operating rules of the laboratories of the Faculty of Biosciences.
1.4 - OTHER CONSIDERATIONS:
2 - SINGLE EVALUATION
Students who opt for single assessment must request it within the deadline and in the manner indicated by the Faculty.
2.1 - THEORY AND PROBLEMS:
This part represents 80% of the final grade of the subject, and will be evaluated by:
Single exam of theory and problems: The singleevaluation of theory and problems will consist of an exam that will be held on the day of the 2nd partial test of the subject and will consist of:
Theory and problem retake exam: The retake of the single assessment will be on the same day and time as the continuous assessment retake test.
2.2 - LABORATORY PRACTICES:
2.3 - OTHER CONSIDERATIONS:
Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. 2016. Biología Molecular de la Célula. 6ª Edición. Editorial Omega.
Alberts B, Heald R, Johnson A, Morgan D, Raff M, Roberts K, Walter P, Wilson J, Hunt T. 2022. Molecular Biology of the cell. 7th Edition. W.W. Norton & Co.
E-book: ISBN: 978-0-393-42708-0: https://wwnorton.com/books/9780393884821
Alberts B, Bray D, Hopkin K, Johnson A, Lewis J, Raff M, Roberts K, Walter P. 2011. Introducción a la Biología Celular. 3ª Edición. Editorial Médica Panamericana.
Lodish H, Berk A, Kaiser CA, Krieger M, Bretscher A, Ploegh H, Martin K, Yaffe M, Amon A,. 2021. Molecular Cell Biology. 8th Edition. Editorial macmillan.
E-book: ISBN:9781319365028: https://store.macmillanlearning.com/ca/product/Molecular-Cell-Biology/p/1319208525#format01
Lodish H, Berk A, Kaiser CA, Krieger M, Bretscher A, Ploegh H, Amon A, Scott MP,. 2016. Biología Celular y Molecular. 7ª Edition. Editorial Panamericana.
Karp G, Iwasa J, Marshall W. 2019. Biología Celular y Molecular. 8ª Edición. Editorial Mc Graw-Hill.
Karp G, Iwasa J, Marshall W. 2018. Karp's Cell Biology, Global Edition. Editorial Wiley.
E-book: Karp G, Iwasa J, Marshall W. 2021. Karp’s Cell and Molecular Biology. 9th Edition. Editorial Willey
Some of the recommended books can be partially accessed online:
Alberts (Molecular Biology of the Cell, 4th Ed.): http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=mboc4
Cooper (The Cell, 2nd Ed.): http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=cooper
There are no specific requirements of programs / software in this subject.
Please note that this information is provisional until 30 November 2025. You can check it through this link. To consult the language you will need to enter the CODE of the subject.
Name | Group | Language | Semester | Turn |
---|---|---|---|---|
(PAUL) Classroom practices | 1 | Catalan | first semester | afternoon |
(PLAB) Practical laboratories | 1 | Catalan | first semester | morning-mixed |
(PLAB) Practical laboratories | 2 | Catalan | first semester | morning-mixed |
(PLAB) Practical laboratories | 3 | Catalan | first semester | morning-mixed |
(PLAB) Practical laboratories | 4 | Catalan | first semester | morning-mixed |
(TE) Theory | 1 | Catalan | first semester | afternoon |