Degree | Type | Year | Semester |
---|---|---|---|
2502442 Medicine | OB | 5 | 2 |
It is absolutely necessary to have achieved sufficient knowledge in general pharmacology.
It is advisable that the student has achieved basic competencies in physiopathology and clinical semiology.
The course is scheduled in the fifth year of the Degree in Medicine, when the students have already achieved knowledge of general pathology and etiology, clinical and diagnostic of the main diseases and syndromes. The student already has a knowledge of the principles of general pharmacology and knows the large groups of medicines, their mechanism of action and the main desired and undesired effects.
The training objectives of the subject are to provide the elements to learn to select the most appropriate treatment for each individual patient through a reasoned process that involves assessing the effectiveness, toxicity, convenience and cost of each available option. Additionally, it is intended to publicize the dynamics of medicines in society, from the search for new molecules to approval by health authorities and pharmacovigilance after marketing, as well as providing the necessary elements to be able to critically evaluate the information about the new medicines that are commercialized.
The theoretical knowledge of the subject is complemented by practical activities on selection of treatments in patients with frequent pathologies, critical evaluation of information on new drugs, and identification and assessment of suspected adverse reactions to drugs in specific patients.
Introduction to Clinical and Therapeutic Pharmacology. The medicines for human use. Sources of information in Clinical Pharmacology. Development of medicines: scientific, methodological, bioethical and legal aspects. Clinical trial of medicines and their methodological bases. Placebo effect. Clinical pharmacokinetics and dose adjustment. Evaluation of the action and effect of medications. Pharmacological interactions of clinical interest and interactions between drugs and other compounds. Adverse drug reactions and pharmacovigilance. Poisoning by drugs and drugs. Clinical pharmacology of pregnancy, childhood and old age. Clinical Pharmacology of renal, cardiac insufficiency and other pathological processes. Pharmacogenetics and pharmacogenomics. Social pharmacology. Pharmacological anamnesis, self-medication and compliance. Legal regulation of medicines and pharmaceutical advertising. Principles of Pharmacoeconomics. Good practices for prescribing medicines. Pharmacoepidemiology. Alternative medicines Selection and prescription of drugs in the main pathological processes in primary care. Regulation of fertility. Pathology of the main devices, organs and systems induced by drugs.
Distributive blocks
A. General clinical pharmacology. The medicines for human use. Information sources.
B. Research methods of new medicines. The clinical trial Methodological and ethical aspects. Evaluation of the effects of medications. Adverse reactions and interactions.
C. Use of drugs in special populations (pregnancy, childhood and old age, renal and cardiac insufficiency).
D. Social pharmacology. Principles of pharmacoeconomics.
E. Special clinical pharmacology - Therapeutics in the most frequent pathologies in primary care.
THEORY
Day 1: Introduction to clinical and therapeutic pharmacology. The medicines for human use.
Day 2: Information sources in clinical pharmacology.
Day 3: Development of medicines: scientific, methodological, bioethical and legal aspects. Placebo effect.
Day 4: Clinical trial of medicines (AC) and its methodological bases (1).
Day 5: AC and its methodological bases (2).
Day 6: Clinical pharmacokinetics and dose adjustment. Evaluation of the action and effect of medications.
Day 7: Pharmacological interactions of clinical interest and interactions between drugs and other compounds.
Day 8: Adverse drug reactions and pharmacovigilance.
Day 9: Pharmacoepidemiology.
Day 10: Use of medications in the health system and its economic implications.
Day 11: Abuse and dependencies of medicines and drugs.
Day 12: Clinical pharmacology of pregnancy and childhood.
Day 13: Clinical pharmacology of old age.
Day 14: Clinical Pharmacology of renal, hepatic and other pathological conditions.
Day 15: Pharmacogenetics.
Day 16: Good practices of prescribing medications. Legal regulation of medicines and pharmaceutical advertising. Anamnesis.
Day 17: Selection and prescription of drugs in the main pathological processes in primary care (1): Introduction to antibiotics.
Day 18: Selection and prescription of drugs in the main pathological processes in primary care (2): Cardiovascular.
Day 19: Selection and prescription of drugs in the main pathological processes in primary care (3): Introduction to psychiatric pathologies.
Day 20: Selection and prescription of drugs in the main pathological processes in primary care (4): Introduction to the treatment of pain.
Day 21: Selection and prescription of drugs in the main pathological processes (5): Oncology.
Day 22: Regulation of fertility.
Day 23: Alternative medicines.
Day 24: Principles of selection and appropriate use of medicines used in respiratory pathology.
Day 25: Principles of selection and appropriate use of medicines used in digestive pathology.
Day 26: Principles of selection and appropriate use of drugs used in genitourinary pathology.
Day 27: Principles of selection and appropriate use of medicines used in elderly patients.
Day 28: Is it possible to depress medications?
SEMINARS OF CLINICAL CASES
Day 1: Information sources in Clinical Pharmacology.
Day 2: Clinical trial of medicines and their methodological bases. Placebo effect
Day 3: Adverse Drug Reactions and Pharmacovigilance
Day 4: The process of drug selection.
Day 5: Prescription of medicines and the health system. Advertising and media communication.
Day 6: Use of drugs in special populations (renal / hepatic insufficiency).
Day 7: Antibiotics (urinary infection and pneumonia).
Day 8: Cardiovascular-I
Day 9: Cardiovascular-II
Day 10: Respiratory
Day 11: Diabetes
Day 12: Psychiatric diseases
Day 13: Polypharmacy
Day 14: Dementia
Day 15: Acute pain
Day 16: Chronic pain
Day 17: Alternative medicines
This Guide describes the framework, contents, methodology and general rules of the subject, in accordance with the current curriculum. The final organization of the subject in relation to the number and size of groups, distribution in the calendar and dates of exams, specific criteria for evaluation and review of exams, will be specified in each of the Hospital Teaching Units (UDH), which they will make explicit in their web pages and the first day of class of each subject, through the teacher responsible for the subject in the UDH.
For the 2015-2016 academic year, the professors appointed by the Departments as responsible for the subject at the Faculty and the UDH level are:
Department responsible: Department of Pharmacology, Therapeutics and Toxicology
Head of the Faculty: Eduardo Diogène Fadini (eduard.diogene@uab.cat)
Responsibles UDH
Responsibles UDHSP |
Responsibles UDHVH |
Responsibles UDGTiP |
Responsibles UDHPT |
Josep Torrent josep.torrent@uab.cat |
Eduardo Diogène Fadini eduard.diogene@iuab.cat |
Magí Farré
|
Caridad Pontes García Cpontes@tauli.cat |
General teaching methodology:
Credits subject: 5.5 ECTS = 137.5 hours
AUTONOMOUS WORK (50% total = 69 hours).
Comprehensive reading of texts and articles, study and realization of schemes, summary and conceptual assimilation of the contents. Preparation of presentations and deliveries.
EVALUATION (5% total = 6.5 hours): 2 partial exams and 1 final synthesis exam, continuous evaluation of the seminars.
DIRECTED TEACHING TYPOLOGIES: up to 45% total 62 hours
Theory (TE typology). Group size: registration group. Scheduled sessions 28 (1h per session).
Clinical practices (PCA typology):
Clinical case seminars (SCC) also includes problem-based learning (PBL) activities. Group size: 2-10 students. Scheduled sessions: 17 sessions of 2 hours. The students, in small groups, will discuss typical clinical assumptions, under the direction of a tutor.
In the current exceptional circumstances, at the discretion of the teachers and also depending on the resources available and the public health situation, some of the theoretical classes, practicals and seminars organized by the Teaching Units may be taught either in person or virtually.
Annotation: Within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.
Title | Hours | ECTS | Learning Outcomes |
---|---|---|---|
Type: Directed | |||
Clinical cases workshops | 34 | 1.36 | 35, 3, 36, 10, 11, 25, 24, 31, 26, 29, 33, 28, 30, 27, 4, 41 |
Theoretical lectures | 28 | 1.12 | 1, 36, 37, 7, 8, 9, 10, 6, 5, 15, 14, 18, 19, 20, 12, 13, 17, 21, 22, 23, 25, 34, 32, 33, 28, 30, 40, 27 |
Type: Autonomous | |||
Personal study time | 36 | 1.44 | 38, 39 |
Readings:articles and reports | 17 | 0.68 | 11, 24, 31, 26, 38, 2, 41 |
Reports and essays | 16 | 0.64 | 11, 24, 31, 26, 38, 41 |
The evaluation system will be based on a theoretical part (70% of the final grade) and a practical part (30% of the final grade).
For the theoretical part:
Two partial theoretical examinations will be programmed, of eliminatory type when the obtained grade is superior to 5.0.
For the practical part:
Attendance at practices is mandatory. According to the particularities of each Teaching Unit, the practices / seminars can be evaluated continuously. According to the UDH, complementary practical activities can be carried out. The continuous evaluation will be specified in the program of each HDU.
The student who has not passed the partial exams and / or has not passed the practices, can submit to the final test of recovery that contains a theoretical part and a practical part.
Final score
The final grade is the weighted average of the theoretical knowledge (70%) and the clinical evaluation (30%). The average between the theoretical evaluation and the clinical evaluation can not be made if a minimum score of 5/10 is not obtained in both tests. In case of not being able to do the average, the final qualification will correspond to the lowest quantitative value among those obtained in the theoretical and clinical evaluations.
When the student does not show up for the scheduled partial tests or the recovery test, it will be considered non-evaluable.
Title | Weighting | Hours | ECTS | Learning Outcomes |
---|---|---|---|---|
Practical cases and problem solving tests | 30 | 3.5 | 0.14 | 35, 3, 36, 10, 11, 25, 24, 31, 26, 29, 33, 28, 30, 38, 39, 27, 4, 2, 41 |
Written assessment by objective test | 70 | 3 | 0.12 | 1, 36, 37, 7, 8, 9, 10, 6, 5, 15, 14, 18, 19, 20, 12, 13, 16, 17, 21, 22, 23, 25, 34, 32, 33, 28, 30, 38, 39, 40, 27 |
Specific bibliography
Rang HP, Dale MM, Ritter JM, Flower R. Rang & Dale’s Pharmacology. 7th ed. Elsevier, Philadelphia, 2012.
Wecker L (ed.) Brody’s Human Pharmacology. Molecular to clinical. 6th ed. Mosby Elsevier, Canadà, 2018.
Reference bibliography
Baños JE, Farré M. Principios de Farmacología clínica, Masson, Barcelona, 2002.
Brunton L, Lazo J, Parker K (Eds.). Goodman & Gilman's The Pharmacological Basis of Therapeutics, 13ed. Mc Graw Hill, Nova York, 2018.
No cal programari específic