Degree | Type | Year | Semester |
---|---|---|---|
4313794 Biochemistry, Molecular Biology and Biomedicine | OT | 0 | A |
The main objective of the module is reviewing the progress made recently in the area of Clinical Biochemistry and Molecular Pathology. It is intended, therefore, that students understand and visualize this using examples, that are not intended to be exhaustive, so they understand how what is the way in which the applications in the area of Laboratory Medicine (specialty Molecular Pathology and Clinical Biochemistry) are generated and applied. The contents will be selected among those advances which, although recent, have proven practical importance. The theoretical instruction is supplemented by expert seminars, discussion of articles and resolution of clinical cases.
CONTENT M 9 |
MASTER IN BIOCHEMISTY, MOLECULAR BIOLOGY AND BIOMEDICINE |
Room |
Place |
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Wednesday, nov 3 |
Introduction. Academic and job oportunities in Clinical Biochemistry and Molecular Pathology |
F. Blanco |
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Unitat Docent Sant Pau |
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Friday, nov 5 |
INVITED CONFERENCE: Molecular basis of complex diseases |
J.M. Soria |
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Unitat Docent Sant Pau |
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Monday, nov 8 |
STANDARDIZATION AND QUALITY (tema I) |
F. Canalias |
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Unitat Docent Sant Pau |
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Wednesday, nov 10 |
Standardization and quality |
F. Canalias |
|
Unitat Docent Sant Pau |
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Friday, nov 12 |
Standardization and quality |
F. Canalias |
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Unitat Docent Sant Pau |
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Monday, nov 15 |
SEMINAR 1. Mass spectrometry: basis and clinical applications |
E. Zapico |
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Unitat Docent Sant Pau |
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Wednesday, nov 17 |
LIPIDS, LIPOPROTEINS AND ARTERIOSCLEROSIS (topic II): Familial Hipercholesterolemia |
F. Blanco |
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Unitat Docent Sant Pau |
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Friday, nov 19 |
SEMINARS 2-3. Animal models of arteriosclerosis. Cellular and molecular biology of arteriosclerosis |
J.C. Escolà / J.L. Sánchez |
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Unitat Docent Sant Pau |
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Monday, nov 22 |
SEMINARIS 3-4. MicroRNAs in cardiovascular research. Novel experrimental aproaches in obesity and diabetes i obesitat.Discussion of papers related to seminar 1 (first part) and topic II and seminars 2 and 3 (second part) |
N. Rotllan / J. Julve |
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Unitat Docent Sant Pau |
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Wednesday, nov 24 |
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E. Zapico / F Blanco | Unitat Docent Sant Pau | |||
Friday, nov 26 |
VIRAL HEPATITIS (topic III). Discussion clinical cases and/or papers |
F. Rodriguez Frias |
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Unitat Docent Sant Pau |
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Monday, nov 29 |
CONGENITAL ERRORS OF METABOLISM (topic IV)
|
M. Tondo |
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Unitat Docent Sant Pau |
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Wednesday, des 1 |
PRENATAL SCREENING (topic V) |
J. Mora |
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Unitat Docent Sant Pau |
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Friday, des 3 |
TUMOR MARKERS (topic VI). Discussion of clinical cases and/or papers |
J. Mora |
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Unitat Docent Sant Pau |
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Friday, des 10 |
BIOCHEMICAL MARKERS OF HEART DAMAGE (topic VII). Biochemical diagnosis of acute myocardial infarction. Biochemical diagnosis of heart failure |
A. García Osuna |
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Unitat Docent Sant Pau |
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Wednesday, des 13 |
BIOCHEMICAL DIAGNOSIS OF ALZHEIMER DISEASE (topic VIII) (first part). Discussion of papers and clinical cases related to topics III and VII |
M. Tondo /F. Blanco |
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Friday, des 15 |
Presentation and defense of papers or clinical cases by the alumni |
J. Mora /F. Blanco |
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Unitat Docent Sant Pau |
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Monday, des 17 |
Presentation and defense of papers or clinical cases by the alumni |
J. Mora / F. Blanco |
|
Unitat Docent Sant Pau |
Class timing: 4-6.30 PM
Classes are planned to be at the Unitat Docent Sant Pau, inside the Hospital Santa Creu i Sant Pau Campus in the city of Barcelona. Closest metro station: Guinardó-Sant Pau, yelow line.
M9 coordinator: F. Blanco Vaca. Phone 93-5537377; email: fblancova@santpau.cat
*Planned M9 program, unless the requirements enforced by the health authorities demand a prioritization or reduction of these contents.
Methodology includes autonomous activities (studying: 106.5 h), supervised activities (study of clinical cases and reading scientific papers for class discussion: 67.5 h) and directed activities (theoretical lessons, seminars, aula practicum: 50 h).
* The proposed teaching methodology may experience some modifications depending on the restrictions to face-to-face activities enforced by health authorities.
Annotation: Within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.
Title | Hours | ECTS | Learning Outcomes |
---|---|---|---|
Type: Directed | |||
theoretical lessons, seminars, aula practicum: 45 h | 7.5 | 0.3 | 4, 3, 5, 6, 8, 7, 10, 2, 9, 11 |
theoretical lessons, seminars, aula practicum: 45 h | 15 | 0.6 | 4, 5, 6, 8, 7, 10, 1, 2, 9, 13, 11, 12, 14 |
theoretical lessons, seminars, aula practicum: 45 h | 22.5 | 0.9 | 4, 5, 7, 2, 9, 11 |
Type: Supervised | |||
Study of clinical cases and reading scientific papers for class discussion: 67.5 h | 67.5 | 2.7 | 4, 3, 5, 6, 8, 7, 10, 1, 2, 9, 13, 11, 12, 14 |
Type: Autonomous | |||
Study: 106.5 h | 106.5 | 4.26 | 4, 3, 5, 6, 8, 7, 10, 2, 9, 13, 11, 12, 14 |
The continous evaluation process must include a minimum of three evaluation activities, of two different types, distributed throughout the course, none of which can represent more than 50% of the final grade
The evaluation will be based on: oral presentation of projects or clinical cases analysis (40% of the grade), presentation of small works and reports, as well as the answer to short exams (30% of the grade) and attendance to class and active participation (30 % of the grade)
Students who do not perform both theoretical and practical tests will be considered as "not presented", therrefore exhausting the rights of the registration.
If plagiarism is detected in any of the works delivered, this may mean that the student suspends the entire module or subject.
PROOF OF RECOVERY AND QUALIFICATION OF NOT EVALUABLE
To participate in exam recovery, students must have been previously evaluated in a set of activities, whose weight equals a minimum of 2/3 parts of the total grade of the subject or module. Therefore, the students will obtain a "Not Evaluable" qualification when the evaluation activities carried out have a weight lower than 67% of the final grade.
Title | Weighting | Hours | ECTS | Learning Outcomes |
---|---|---|---|---|
Attendance and active participation in classes | 30% | 0 | 0 | 4, 3, 5, 6, 8, 7, 10, 1, 2, 9, 13, 11, 12, 14 |
Oral presentation of projects or clinical cases | 40% | 4 | 0.16 | 4, 3, 6, 8, 7, 10, 1, 2, 9, 11, 12, 14 |
Presentation of homework and reports, small exams of short questions (in writing) | 30% | 2 | 0.08 | 3, 6, 8, 7, 10, 1, 2, 11, 12, 14 |
TEXTBOOKS:
1) Tietz texbook of Clinical Chemistry and Molecular Diagnostics. Burtis CA, Ashwood ER, Bruns DE eds. Elsevier, 2014.
2) Molecular Basis of Inherited Disease. Valle, Beaudet, Vogelstein et al. Saunders 2001 (digital edition with timely actualization: https://ommbid.mhmedical.com/ommbid-index.aspx).
SCIENTIFIC JOURNALS (Some of these journals allow public or limited access through intenet, or through the UAB website*):
1) Clinical Chemistry. http://search.ebscohost.com/direct.asp?db=ccm&jid=%2210CS%22&scope=site
2) Clinica Chimica Acta, https://www.sciencedirect.com/science/journal/00098981
3) Clinical Biochemistry, https://www.sciencedirect.com/science/journal/00099120
4) Circulation, http://ovidsp.ovid.com/ovidweb.cgi?T=JS&MODE=ovid&NEWS=n&PAGE=toc&D=ovft&AN=00003017-000000000-00000
5) Blood, https://ashpublications.org/blood/issue-covers/volume/
6) Journal of Lipid Research, http://www.jlr.org/
7) New England Journal of Medicine, http://www.nejm.org/
8) Lancet, http://search.ebscohost.com/direct.asp?db=ccm&jid=%22LAN%22&scope=site
9) Journal of Clinical Investigation, http://www.jci.org/
1) Cell Metabolism, http://www.cell.chttp://www.jci.orgom/cell-metabolism/redirectUrl/
12) Nature Medicine, http://www.nature.com/nm/index.html
14) Cancer Research, http://cancerres.aacrjournals.org/
*For more information, go to the digital UAB library M9 page: https://catalegclassic.uab.cat/search~S1*spi?/pBLANCO+VACA%2C+FRANCISCO/pblanco+vaca+francisco/-3%2C-1%2C0%2CB/frameset&FF=pblanco+vaca+francisco&5%2C%2C5
SCIENTIFIC CLINICAL LABORATORY SOCIETY WEBSITES:
1) American Association for Clinical Chemistry, www.aacc.org
2) Associació Catalana de Ciències de Laboratori Clínic, www.acclc.cat
3) International Federation of Clinical Chemistry and Laboratory Medicine, www.ifcc.org
4) Sociedad española de Química Clínica y Patología Molecular, www.seqc.es
No especific software is used