Degree | Type | Year | Semester |
---|---|---|---|
2501230 Biomedical Sciences | OT | 4 | 0 |
General concepts related to physiology and biochemistry.
Study of the components of biological membranes and their molecular organization.
Structural and dynamic features of the two main components of biological membranes: lipids and proteins, establishing the links between their molecular structure and physiological functions and possible associated pathologies.
Unravel the molecular mechanisms of vital functions like the propagation of nerve impulse and signal transduction through cellular envelopes or the transport of molecules across biological membranes.
Methods and techniques used for the study of biomembranes.
1. Introduction
2. Biomembranes
2.1. Structure and function of biological membranes
2.2. Biophysical properties of biological membranes
2.3. Classification and composition of biologigal membranes
3. Lipids and tensioctives
3.1. Structural and biophysical properties of membrane lipids
3.2. Preparation and types of lipid vesicles
3.3. Tensioactives and detergents: efects on biological membranes
4. Membrane proteins
4.1. Classification and types of membrane proteins
4.2. Structural principles of membrane proteins
4.3. Biogenesis and folding of membrane proteins
4.4. Modification of membrane proteins
4.5. Membrane proteins-biologcal membranes interactions
4.6. Transport across membranes
4.7. Membrane fluidity amd membrane protein function
5. Methods in biomembranes
6. Specialized seminars performed by students
* Unless the requirements enforced by the health authorities demand a prioritization or reduction of these contents.
The theory classes will be in complete groups.*
There will be seminars in which students will present individually or in small groups, subjects related to different aspects of the structure and function of the biological membranes.
Attendance at the seminars will be monitored, and the mark obtained will be considered only when attendance is equal to or greater than 80 % of the seminars.
The practical classes will consist of:
A) 2 laboratory sessions:
B) 1 supervised non-contact bioinformatic work.
* The proposed teaching methodology may experience some modifications depending on the restrictions to face-to-face activities enforced by health authorities.
Title | Hours | ECTS | Learning Outcomes |
---|---|---|---|
Type: Directed | |||
Master class with IT support | 35 | 1.4 | 2, 3, 4, 12 |
Seminars regarding subject main topics. Discussion of topics. | 7 | 0.28 | 3, 4, 12 |
Type: Supervised | |||
Laboratory practical sessions | 8 | 0.32 | |
Tutoring sessions | 6 | 0.24 | 3, 12 |
Type: Autonomous | |||
Autonomous study | 53 | 2.12 | 3 |
Bibliography search and seminar preparation | 30 | 1.2 | 3, 4 |
Deliverables | 2 | 0.08 |
The evaluation will consist of four parts that make up a continuous evaluation process which includes:*
a) two partial exams of the theoretical knowledge subject (70%).
b) the laboratory practices (14%).
c) the works proposed throughout the course (10%).
d) the seminars (6 %), in the case of complying with the assistance indicated in Methodology (equal to or greater than 80 % of the seminars).
A minimum passing grade of 4 in each one of the two theoretical exams is required to pass the subject.
Students who have not passed some of them will take a new exam about of the parts not passed.
Students who want to upload the grade can take a global exam of the whole subject, which will provide the final grade.
Test
The exams will combine multi-choice test questions (60%) with short questions (40%) about the master classes.
Laboratory practices will be evaluated by a report (14%).
In relation to the evaluation of works to be delivered throughout the course and a bioinformatic work supervised with a questionnaire that must also be submitted (10% of the final grade).
The seminars will be evaluated based on the work presented by the student (6% of the final grade).
Final mark
Weighted mean of a) to d). To pass the subject the overall mark should be 5.0 or higher.
Exam Review
On-demand exam reviewing will be done individually with the student.
* Student’s assessment may experience some modifications dependingon the restrictions to face-to-face activities enforced by health authorities.
Title | Weighting | Hours | ECTS | Learning Outcomes |
---|---|---|---|---|
Evaluation of deliverables | 10% | 2 | 0.08 | 1, 11, 2, 4, 5, 10, 9, 8, 6, 7 |
Evaluation of oral presentations | 6% | 3 | 0.12 | 3, 4, 12 |
Evaluation of practical sessions | 14% | 1 | 0.04 | 1, 11, 4, 5, 10, 9, 8, 6, 7, 12 |
Evaluation of theoretical knowledge. Short answer test and multiple-choice test. | 70% (Multiple-choice 60% + Short-answer 40%) | 3 | 0.12 | 3, 12 |
The Structure of Biological Membranes (2nd edition)
Editor: P. Yeagle. CRC Press, (2005): Biblioteca Ciències
Biomembranes
Gennis, R.B. Springer-Verlag, (1989): Biblioteca Ciències
Liposomes: a practical approach
Editor: R.R.C. New, IRL Press (Oxford) (1990)
Dynamics of Biological Membranes
Houslay, M.D., Stanley, K.K. John Wiley & Sons, (1982)
Introduction to Biological Membranes
Jain, M.K. John Wiley & Sons, 2nd ed., (1988): Biblioteca Ciències
Biophysical Chemistry of Membrane Functions
Kotyk, A., Janácek, K., Koryta, J. John Wiley & Sons, (1988): Biblioteca Ciències