Analysis and Synthesis of Bioprocesses
Code: 100962 ECTS Credits: 6| Degree | Type | Year |
|---|---|---|
| 2500253 Biotechnology | OB | 3 |
Contact
- Name:
- Pau Ferrer Alegre
- Email:
- pau.ferrer@uab.cat
Teaching groups languages
You can view this information at the end of this document.
Prerequisites
The syllabus does not determine any specific prerequisite for this subject. However, due to its integrating nature of the different knowledge acquired throughout previous courses, the recommendation is to have passed the maximum number of subjects possible before taking it. In any case, they are essential to be able to properly follow the basic principles of bioprocess engineering, bioreactors and separation and purification processes.
Objectives and Contextualisation
Acquire comprehension and practice in the analysis of biotechnological processes in terms of engineering, economics, compliance with regulations, quality, intellectual property, etc.
Introduce to the student the most important tools used in the analysis and to be able to use these tools in the evaluation and comparison of different solutions (proposals) of design of a determined process.
Overall, it is a subject where we intend to integrate / synthesize knowledge acquired in other subjects of the degree for the design (synthesis and analysis) of bioprocesses.
Learning Outcomes
- CM20 (Competence) Propose the appropriate design of a bioreactor according to its application.
- CM20 (Competence) Propose the appropriate design of a bioreactor according to its application.
- CM21 (Competence) Design an industrial process taking into account ethical and sustainable development aspects.
- KM21 (Knowledge) Illustrate an industrial process for obtaining products by biotechnological means from basic discovery to market introduction.
- KM21 (Knowledge) Illustrate an industrial process for obtaining products through biotechnological means, from basic discovery to market introduction.
- SM18 (Skill) Apply the kinetic and enzymatic methods necessary for the operation of a bioreactor.
- SM19 (Skill) Use a bioreactor appropriately.
- SM19 (Skill) Use a bioreactor appropriately.
Content
1. Analysis of bioprocesses
1.1. Characteristics of the biotechnological industries.
1.2. Structure of bioprocesses. The stages of the development and design of a process.
1.3. Analysis of bioprocesses: Economic, environmental and social sustainability assessment.
2. Synthesis of bioprocesses: Selection, arrangement and integration of steps of bioprocesses
2.1. Synthesis of the biocatalyst.
2.2. Synthesis of upstream stages and of the cultivation/bioreaction system and strategy.
2.3. Synthesis of the recovery and purification stages of the product.
2.4. Bioprocess integration and intensification. Biorefineries
2.5. The quality of the process and product.
3. Design of bioprocesses:
3.1. Biotechnology applied to human and animal health.
3.2. Industrial biotechnology and agro-food.
3.3. Environmental biotechnology.
Activities and Methodology
| Title | Hours | ECTS | Learning Outcomes |
|---|---|---|---|
| Type: Directed | |||
| Seminars | 15 | 0.6 | CM20, CM21, KM21, SM18 |
| Theoretical classes | 30 | 1.2 | CM20, CM21, KM21, SM18, SM19 |
| Type: Supervised | |||
| Compulsory group work | 50 | 2 | CM20, CM21, KM21, SM18, SM19 |
| Type: Autonomous | |||
| self study | 47 | 1.88 | CM20, CM21, KM21, SM18 |
Teaching will be carried out with face-to-face theoretical classes.
In addition to the theoretical classes, seminars will be held on specific aspects of bioprocesses, applied to health, industrial (chemical, etc.), agrofood and environmental. Students, working in groups of 4 or 5, will have to carry out a study on a
biotechnological process case introduced in the seminars, of their choice. They will presented a writen report on the case study, which will be further discussed in the seminar sessions.
The subject is registered in the Virtual Campus and all the materials used in the classes and seminars will be deposited, as well as some articles that will allow students who are interested in deepening their knowledge
in a specific topic.
Annotation: Within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.
Assessment
Continous Assessment Activities
| Title | Weighting | Hours | ECTS | Learning Outcomes |
|---|---|---|---|---|
| Compulsory group work | 25% | 0 | 0 | CM20, CM21, KM21, SM18 |
| Partial exams | 75% | 6 | 0.24 | CM20, CM21, KM21, SM18, SM19 |
| Recovery exam | 75% | 2 | 0.08 | CM20, CM21, KM21, SM18, SM19 |
The compulsory group work, selected from the 4 case studies of the syllabus presented in the Seminars sessions, will represent 25% of the final grade.
To participate in the recovery exam, the students must have previously been evaluated in a set of activities whose weight equals to a minimum of two thirds of the total grade of the subject or module. Therefore, students will obtain the "Non-Valuable" qualification when the evaluation activities carried out have a weighting of less than 67% in the final grade
Students who do not pass the partial examinations may perform a recovery exam of the whole theoretical part, which will have a weight of 75% (which will be added to the the compulsory group work assessment with a 25% weight that is not recoverable).
Single-call evaluation
The single-call evaluation consists of a single synthesis exam that covers the whole theory program of the subject (that is, it replaces the three partial exams). The synthesis exam will have the same type of questions as the partial exams. This exam will have a weight of 75 % of the overall subject.
Students that choose the single-call evaluation modality must participate in the group work case study. The evaluation and weight on the overal grade of the group work assignement will be the same as for the continuous evaluation modality (25%).
The syntesis exam will bescheduled on the same day that the last partial exam of the continuous evaluation, and the same second-chance examination procedure will apply.
To pass the subject, a minimum grade of 4 (over 10) must be achieved in the synthesis exam.
Bibliography
- Heinzle E., Biwer A., Cooney C. 2006. Development of Sustainable Bioprocesses:Modelling and Assessment. John Wiley & Sons, Ltd. (ref. biblioteca UAB: 66.09, CDROM:RED/674).
- Atkinson B., Mavituna F. 1991. Biochemical Engineering and Biotechnology Handbook. (ref. biblioteca UAB: 66.09Atk)
- Flickinger M.C., Drew S.W. 1999. Encyclopedia of Bioprocess Technology:Fermentation, Biocatalysis and Bioseparation. John Wiley and Sons, Inc. (ref. bibliotecaUAB: 66.09)
- Turton R., Bailie R.C., Whiting W.B., Shaeiwitz J.A. 2003. Analysis, synthesis, and design of chemical processes. 2nd edition. Prentice Hall PTR. (ref. biblioteca UAB: 66.02Ana)
- Biotechnology: a multi-volume comprehensive treatise (edited by H.J. Rehm and G. Reed) 2nd completely revised edition. Weinheim, VCH, 1993-2001 (ref. biblioteca UAB: 5(03) 79 Bio).
- Kirk-Othmer Encyclopedia of Chemical Technology (recurs electrònic) (Accés restringit als usuaris de la UAB: http://onlinelibrary.wiley.com/book/10.1002/0471238961)
Software
In order to elaborate and present the assay on the case study, alumni will have to use a standard ofimatics software
Language list
| Name | Group | Language | Semester | Turn |
|---|---|---|---|---|
| (SEM) Seminars | 431 | Catalan | second semester | morning-mixed |
| (SEM) Seminars | 432 | Catalan | second semester | morning-mixed |
| (SEM) Seminars | 433 | Catalan | second semester | morning-mixed |
| (SEM) Seminars | 434 | Catalan | second semester | morning-mixed |
| (TE) Theory | 43 | Catalan | second semester | morning-mixed |