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2022/2023

Integrated Process Design

Code: 43327 ECTS Credits: 6
Degree Type Year Semester
4314579 Biological and Environmental Engineering OB 1 2

Contact

Name:
Teresa Gea Leiva
Email:
teresa.gea@uab.cat

Use of Languages

Principal working language:
spanish (spa)

Teachers

Adriana Artola Casacuberta
Alfred Fernandez Castane

Prerequisites

None

Objectives and Contextualisation

To combine chemical, biological and environmental engineering principles, tools and methodologies for the integrated design and intensification of processes, aiming to the design of economically, energetically and environmentally efficient and sustainable processes. 

The learning objectives therefore include identifying and applying criteria (techno economic and environmental) and different approaches to define/select optimal sequences of operations for biotechnological and environmental processes, as well as their integration into biorefineries, with special emphasis in the separation operations and strategies for process intensification.

 

 
 
 
 

Competences

  • Apply methods, tools and strategies to develop biotechnological processes and products with energy-saving and sustainability criteria.
  • Apply specific methodologies, techniques and resources to conduct research and produce innovative results in the area of biological and environmental engineering.
  • Continue the learning process, to a large extent autonomously.
  • Define and design the characteristic separation sequences in chemical, biotechnological and environmental processes in order to increase separation yields, applying criteria of energy optimisation.
  • Integrate and use chemical, environmental and/or biological engineering tools to design biological systems for the sustainable processing of waste and/or for industrial biotechnological processes.
  • Integrate knowledge and use it to make judgements in complex situations, with incomplete information, while keeping in mind social and ethical responsibilities.
  • Organise, plan and manage projects.
  • Seek out information in the scientific literature using the appropriate channels and integrate this information, showing a capacity for synthesis, analysis of alternatives and critical debate.
  • Solve problems in new or little-known situations within broader (or multidisciplinary) contexts related to the field of study.
  • Take sex- or gender-based inequalities into consideration when operating within one's own area of knowledge.
  • Use IT tools to acquire further knowledge in the field of biological and environmental engineering.
  • Use acquired knowledge as a basis for originality in the application of ideas, often in a research context.
  • Work in a multidisciplinary team.

Learning Outcomes

  1. Analyse separation operations in biotechnological and environmental processes, solving design and operation problems.
  2. Apply specific methodologies, techniques and resources to conduct research and produce innovative results in the area of biological and environmental engineering.
  3. Continue the learning process, to a large extent autonomously.
  4. Identify the advantages and disadvantages of the different separation sequences in sustainable waste treatment and in industrial biotechnological processes.
  5. Integrate knowledge and use it to make judgements in complex situations, with incomplete information, while keeping in mind social and ethical responsibilities.
  6. Integrate the different stages of a process, choosing the appropriate alternative sequencing.
  7. Optimise processes in terms of energy-use on the basis of an integrated analysis.
  8. Organise, plan and manage projects.
  9. Seek out information in the scientific literature using the appropriate channels and integrate this information, showing a capacity for synthesis, analysis of alternatives and critical debate.
  10. Solve problems in new or little-known situations within broader (or multidisciplinary) contexts related to the field of study.
  11. Take sex- or gender-based inequalities into consideration when operating within one's own area of knowledge.
  12. Use IT tools to acquire further knowledge in the field of biological and environmental engineering.
  13. Use acquired knowledge as a basis for originality in the application of ideas, often in a research context.
  14. Use material transfer criteria in the design of continuous-contact separation operations.
  15. Work in a multidisciplinary team

Content

Unit 1: Introduction. Integrated process design and process intensification concepts. Biorefinery concept.

Unit 2: Bioreactors and operation. Industry 4.0.

Unit 3: Separation operation in biotechnolgical and environmental process engineering. Classification, equipment and use. Calculation methods for design of separation operations.

Unit 4: Integrated design of biotechnological and environmental processes.  Design of biorefineries. Case studies.

Unit 5: Process intensification.  Resources (energy, water, feedstocks) optimisation and waste minimization. Case studies.

 

Methodology

Lectures: Master classes with ICT support.
 
Problem-solving-based and Case study-based teaching: Solving of problems in class and proposal of additional problems. In the case study-based teaching, students work together in small groups on a case study of an integrated bioprocess/biorefinery for the sustainable production of bio-based products (e.g. bioplastics, chemicals, biofuels, etc.), under the supervision of the professors. At the end of the case studies sessions, students will have to explain and discuss key concepts and design solutions with the rest of the class.

 

Annotation: Within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.

Activities

Title Hours ECTS Learning Outcomes
Type: Directed      
Exercise-based and case study-based teaching 12 0.48 1, 2, 9, 4, 6, 15, 14
Lectures 27 1.08 4, 6, 7, 5, 3, 13, 14
Type: Autonomous      
Problem solving and work on case study 32 1.28 1, 2, 9, 4, 6, 5, 3, 13, 15, 14
Study 62 2.48 5, 3

Assessment

Please refer to the Catalan or Spanish version of this document

 

Assessment Activities

Title Weighting Hours ECTS Learning Outcomes
Final exam (individual) 40% 2 0.08 1, 4, 6, 7, 5, 10, 3, 13, 14
Participation in class and activities 20% 5 0.2 1, 2, 9, 4, 6, 7, 3, 15, 14
Presentation and discussion case study 20% 2 0.08 11, 1, 4, 6, 7, 5, 3, 13, 14
Written report case study 20% 8 0.32 2, 9, 4, 6, 8, 5, 3, 13, 15, 12

Bibliography

On-line resources

Integrated Bioprocess Engineering https://app.knovel.com/web/toc.v/cid:kpIBE0002U/viewerType:toc//root_slug:integrated-bioprocess-engineering?kpromoter=marc

Industrial Biotechnology: Products and Processes. https://onlinelibrary.wiley.com/doi/book/10.1002/9783527807833

Continuous Biomanufacturing ‐ Innovative Technologies and Methods. https://onlinelibrary.wiley.com/doi/book/10.1002/9783527699902

Other resources

- Belter PA, Cussler EL, Hu W-S. 1988. Biosepartions. Downstream processing for biotechnology. John Wiley & Sons. ISBN 0-471-84737-2.
 
- Blanch HW, Clark DS. 1996. Biochemical Engineering. Marcel Dekker. ISBN0-8247-8949-0.
 
- Heinzle E, Biwer A, Cooney C. 2006. Development of Sustainable Bioprocesses: Modelling and Assessment. John Wiley & Sons, Ltd.
 
- Harrison RG, Todd PW, Rudge SR, Petrides DP. 2015. Bioseparations Science and Engineering. Oxford University Press. ISBN 978-0-19-539181-7.
 
- Kamm B, Gruber PR, Kamm M (Eds.)  2006. Biorefineries –Industrial Processes and Products. Wiley-VCH Verlag. ISBN 3-527-31027-4.
 
- Marcilla Gomis A. 1999. Introducción a las operaciones de separación de contacto continuo.  Publicacions de la Universitat d'Alacant.
 
- Shuler ML, Kargi F (Eds.) 2002. Bioprocess Engineering. Basic concepts. 2nd Edition. Prentice Hall PTR.  ISBN 0-13-081908-5.
 
- Stuart RT, El-Halwagi MM. 2013. Integrated Biorefineries: Design, Analysis, and Optimization. CRC Press. ISBN 9781439803462.
 
- Ratledge C, Kristiansen B (Eds). 2006. Basic Biotechnology. 3rd Edition. Cambridge University Press.
 
- Recasens Baxarias F. 2018. Procesos deseparación de biotecnología industrial. Publicacions Universitat Politècnica de Catalunya.  Iniciativa Digital Politècnica ebook.
 
-  Shri Ramaswamy; Bandaru V. Ramarao; Hua-Jiang Huang. 2013. Separation and Purification Technologies in Biorefineries. John Wiley & Sons Incorporated. ebook.

Software

No specific software used