Degree | Type | Year | Semester |
---|---|---|---|
2501922 Nanoscience and Nanotechnology | OB | 3 | 1 |
It is recommended to have passed and passed the 2nd year subjects "Chemistry of the Elements", "Organic Chemistry" and "Thermodynamics, Kinetics and Phase Transformations"
Although the classes are in Catalan, much of the material that the student will have to work as well as the main bibliographic sources are written in English. Therefore, good knowledge of this language is recommended.
In this subject, the students will learn the basis of in Supramolecular Chemistry, which will allows them to recognize molecular recognition phenomena from a chemical point of view and to understand
the processes involved in the formation of self-assembled supramolecular structures.
The specific objectives of this subject are:
· To introduce the concept of Supramolecular Chemistry, to study the chemical interactions on which it is based and know the main methods of characterization and manipulation of the supramolecular complexes.
· To apply the basics of Supramolecular Chemistry to the understanding of the processes of molecular recognition both at a chemical and biological level.
· To use the basics of Supramolecular Chemistry to interpret the formation of self-assembled supramolecular structures.
1. Introduction to Supramolecular Chemistry.
Supramolecular systems. Supra molecular forces (van der Waals, hydrogen, ion-ion, ion-dipole, dipole-dipole, ion-π, π-π, hydrophobic). Relationship between strength and directionality. Coordination chemistry: metallic centers and ligands. Basic concepts in supramolecular chemistry: host-guest systems and self-assembling; association constants and selectivity; complementarity, preorganization and cooperativity.
2. Characterization and manipulation of supramolecular systems.
X-ray diffraction. Mass spectrometry. Spectroscopic techniques (UV-vis, IR, NMR). Electrochemical techniques. Electrochemical and photochemical manipulation of supramolecular systems.
3. Complexation and molecular recognition.
Recognition of cations, anions and neutral molecules. Association constants. Stoichiometry. Applications.
4. Self-assembly and self-organization.
Concept of self-assembly and self-organization. Self-assembling based on intermolecular interactions (amphiphilic molecules). Self-assembling based on coordination in metal centers (helicates, racks, ladders, grids). Mechanical self-assembling (rotaxanes, catenanes, knots).
5. Supramolecular interactions and molecular recognition in biological systems. Biological structures and processes based on supramolecular interactions: nucleotides and DNA; peptides and proteins; lipids and membranes; virus.
LAB EXPERIMENTS
Experiment 1. Determination of critical micelle concentration by means of conductivity measurements
Experiment 2. Characterization of the inclusion complex between cyclodextrin and phenolphthalein by means of UV-vis spectroscopy
Experiment 3. Synthesis and characterization of an anion-binding host
The teaching methodology and assessment proposed in the guide may undergo some modification depending on the attendance restrictions imposed by the health authorities.
Students will have to develop different types of activities throughout this course:
a) Guided activities: Theoretical classes and exercises will be held in the classroom. On the other hand,
students will also carry out laboratory experiments consisting of the synthesis and / or characterization of supramolecular systems.
All the materials needed for these activities will be found in the space of the course on the Virtual Campus.
b) Supervised activities: Tutorial classes would be done in order to monitor one of the assessment activities
that students must work on, which consists in reading, understanding and writing a scientific article related to the subject.
c) Autonomous activities: Students will have to study the contents of the course, solve problems,
prepare laboratory experiments, summarize and present a scientific article.
Annotation: Within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.
Title | Hours | ECTS | Learning Outcomes |
---|---|---|---|
Type: Directed | |||
Laboratory teaching | 14 | 0.56 | 1, 17, 4, 23, 18, 15, 16, 5, 33, 20, 25, 26, 27, 22, 29, 31, 34, 6 |
Problems and Exercices | 8 | 0.32 | 1, 2, 7, 4, 9, 8, 10, 11, 12, 14, 16, 24, 25, 27, 28, 13, 32, 34 |
Theoretical classes | 22 | 0.88 | 2, 7, 9, 8, 10, 11, 12, 14, 16, 19, 24, 27, 28 |
Type: Supervised | |||
Tutorial classes | 1 | 0.04 | 4, 21, 18, 16, 19, 31, 34 |
Type: Autonomous | |||
Exercices | 14 | 0.56 | 1, 2, 17, 7, 11, 21, 18, 14, 16, 20, 24, 25, 27, 28, 32, 31 |
Laboratory | 25 | 1 | 2, 17, 7, 12, 21, 18, 14, 16, 19, 20, 24, 25, 27, 28, 13, 34 |
Preparation of laboratory experiments | 2.75 | 0.11 | 18, 16, 33, 19, 20, 29 |
Self study | 33 | 1.32 | 17, 9, 8, 10, 11, 12, 18, 14, 16, 19, 20, 24, 27, 28 |
The evaluation of the students will be realized by means of several evidences:
Written exams: There will be two midterm exams throughout the course, one in the middle and the other at the end of the semester.
Each of these exams will have a weight of 35% on the final grade. If the average mark of these two exams is less than 5,
a final exam will be required at the end of the semester (as long as 2/3 assessment tasks have been passed),
which will include the contents of the whole course, and the mark will equal 70% of the total (i will replace the partial exams).
In order to do the final exam the student will have to appear in both partial sessions. Students who want to improve
their mark may also be present at the final exam; If the mark of this exam is greater than the average of the two partial exams,
then the final exam will equal 70% of the final. Otherwise, the exam grades will correspond to the average of the partial exam
grades and the final exam mark.
Laboratory: Laboratory experiments will be evaluated by carrying out a small written test at the end of the last practice session,
which will be equal to 10% of the final mark of the subject.
Written work on a scientific article: The students will be distributed in groups of 3-5 students
and each of these groups will be assigned a subject related to the contents of the subject.
Students will have to look for a scientific article focused on this topic, read it, analyze it and prepare a presentation
in the English language that will be evaluated. This activity will have a weight of 20% on the final grade of the subject.
In order to pass the subject, students must have:
1) An average grade of exams exceeding 5.
2) An average grade over 5.
3) Have attended the three practice sessions in the laboratory. In the event of having completedless than one third of the evaluable evidence
of the course and / or having failed in an unjustified manner in any of the practice sessions in the laboratory,
the students will be evaluated as "not presented".
Title | Weighting | Hours | ECTS | Learning Outcomes |
---|---|---|---|---|
Laboratory | 10 | 0.25 | 0.01 | 1, 2, 17, 7, 3, 4, 11, 21, 18, 14, 16, 19, 20, 24, 25, 27, 30, 28, 13, 32, 31, 34 |
Presentation of a scientific paper | 20 | 2 | 0.08 | 1, 17, 4, 23, 18, 15, 16, 5, 33, 20, 25, 26, 27, 22, 29, 30, 31, 34, 6 |
Writting Exams | 70% | 3 | 0.12 | 1, 2, 7, 4, 9, 8, 10, 11, 12, 14, 20, 24, 25, 27, 30, 28, 32, 31 |
Teams, Microsolft Office, OBS Studio