Degree | Type | Year | Semester |
---|---|---|---|
2502445 Veterinary Medicine | OB | 3 | A |
PHYSIOLOGY (general concepts on organs and systems functioning)
BIOCHEMISTRY (molecular mechanisms of the basic functions of the organism)
Contextualisation. Third year studies degree (first semester and first half of second semester).
General objectives: Provide the student with the fundamental concepts in the field of pharmacology. Studying drugs, their mechanism of action and their effects, as the basics of therapeutic pharmacology
Educational Objectives: Acquisition of the basic principles of pharmacokinetics (drug delivery, absorption, distribution, metabolism and excretion), and pharmacodynamics (mechanism of action), interactions and adverse drug reactions, underlying the rational and appropriate use of drugs in the different fields of applied pharmacology.
THEORETICAL / PRACTICAL PROGRAM / EXAMS *
THEORY
Introduction to Pharmacology
I. Pharmacokinetics
ADME processes. Drug administration and absorption. Distribution of drugs in the body. Biotransformation of drugs. Drug excretion. Pharmacokinetics.
II. Pharmacodynamics
General principles of drug action. Pharmacological targets: receptors. Type of receptors. Channel-coupled receptors, G protein-coupled receptors, which control gene transcription. Regulation of the receptors: up- and down-regulation. Other pharmacological targets. Antibodies as selective drugs.
III. Factors that limit drug efficacy
Drug interactions. Adverse drug reactions.
IV. Drugs acting on the Autonomous/peripheral Nervous System
General aspects of the pharmacology of the peripheral nervous system. Pharmacology of the cholinergic transmission. Pharmacology of noradrenergic transmission. Pharmacology of the motor plaque.
V. Pharmacology of the Central Nervous System
Central nervous system: general considerations. Analgesics. Sedative and tranquilizer agents. Antidepressants, Antiepileptic and anticonvulsant drugs. Anesthetic drugs.
VI. Anti-inflammatory, anti-allergic and immunomodulatory drugs
Steroids. Non-steroidal anti-inflammatory drugs (NSAIDs). Antihistamine drugs Immunomodulatory drugs. Others agents acting on the immune system.
VII. Anti-infective drugs
General principles of the pharmacology of antimicrobials. Betalactamics: Penicillins and Cephalosporins. . Aminoglycosides and Polypeptides. Quinolones Sulfamides. Tetracyclines and Phenolic. Macrolides and Lincosamines. Antimicotic and antivirals. Antiparasitic agents: Anthelmintics, Ectoparasitic and Antiprotozoa.
VIII. Systemic pharmacology
Drugs that act on the cardiovascular system. Drugs that act on the respiratory system. Drugs that act on hemostasis. Pharmacology of the digestive system. Drugs with diuretic action. Pharmacological regulation of the endocrine system.
IX. Anticancer drugs
Cytotoxic agents and other anticancer.
X. Others
Sources for obtaining new drugs
- PRACTICAL SESSIONS
Routes of Administration (experimental lab). Absorption of drugs (experimental lab). Drug metabolism (experimental lab). Drug excretion (experimental lab). Pharmaceutical Forms and Formulation (on line). Pharmacokinetic cases (classroom). Journal club (classroom). Drug Discovery (computer simulator). Case study 1 (classroom). Neuromuscular Junction (computer science). Case 2 (classroom). Organ bath: cholinergic drugs (experimental lab). Case 3 (classroom). Cardiolab (computer simulator). How to write a scientific article (online).
- EXAMS
3 mid-term exams and one remedial exam
-TEAMS
1 Teams (Introduction)
6 Teams to answer students questions
*Unless the requirements enforced by the health authorities demand a prioritization or reduction of these contents.
- Theory classes: online
- Seminars: The objective is to reinforce some of the concepts that have been developed in theory classes, through practical exercises.
- Practical classes: these are carried out in the experimental laboratory. Students organize themselves to develop the practical experiences where the students learn how to manipulate and administrate the animals under the professor supervision.
- Computer simulations: Here students carry out virtual experiments through Pharmacology programs aimed at reinforcing certain concepts explained in the theoretical program.
- Self-learning: discussion of cases and articles. Students will have to solve on their own account certain cases proposed by the teaching staff, and that they will have to develop in group. A discussion will be made in common. The work groups will be of maximum 3 students and a minimum of 2. In the case of the discussion of articles, the students will have to prepare the oral presentation on different articles proposed by teachers (group work). The work groups will be of maximum 3 students and a minimum of 2.
The proposed teaching methodology may experience some modifications depending on the restrictions to face-to-face activities enforced by health authorities.
Annotation: Within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.
Title | Hours | ECTS | Learning Outcomes |
---|---|---|---|
Type: Directed | |||
Computer simulation | 6 | 0.24 | 2, 4, 5, 7, 10 |
Discussion of articles | 4 | 0.16 | 1, 3, 5, 7, 9, 10 |
Discussion of cases | 6 | 0.24 | 2, 3, 4, 8, 6, 10 |
Practical classes | 10 | 0.4 | 1, 2, 3, 11, 10 |
Seminars | 4 | 0.16 | 2, 5, 6, 9, 10 |
Theoretical Classes (Magistral) | 50 | 2 | 4, 8, 5, 6, 7, 9, 10 |
Type: Autonomous | |||
Preparation work / article / simulations | 29 | 1.16 | 2, 3, 4, 8, 5, 9, 10 |
Study | 111 | 4.44 | 8, 5, 6, 7, 9, 10 |
The assessment system consists of tests related to the theoretical / practical part of the program (lectures, seminars and practices) and self-study (cases, works and discussion of articles). It is mandatory to be able to evaluate having completed at least 90% of the practical program.
Theoretical-practical evaluation:
1. 3 exams with different evaluable activities
2. 6 Team / individual projects.
* Final note:
1. 80% of the tree exams + 20% to the average note of the works
2. Half-notes work: it is necessary that the mark of each part is 4 or higher in order to be able to make the average and obtain the final mark.
To pass the subject, the mean notes obtained in all evaluable activities must be equal to or greater than 5.
Final examination of recovery. This exam must be carried out by students who have not obtained a grade equal to or greater than 4 in all the partial exams or have obtained a final grade (exam + team work) of less than 5, or who wish to improve the grade of a partial one.
Characteristics:
If the mark obtained in the examination of recovery is inferior to the note of the partial one that was tried to surpass, will take into account the highest note.
REPEATERS
The notes of teamwork are not kept from one course to the next to pass the subject.
Student’s assessment may experience some modifications depending on the restrictions to face-to-face activities enforced by health authorities
Title | Weighting | Hours | ECTS | Learning Outcomes |
---|---|---|---|---|
3 Exams | 80% | 3 | 0.12 | 1, 2, 3, 4, 8, 5, 6, 7, 11, 9, 10 |
Cases (3) (evaluated during session) | 3.3 % | 0 | 0 | 1, 2, 3, 4, 8, 5, 6, 7, 11, 9, 10 |
Exam recovery | 80% | 2 | 0.08 | 1, 2, 3, 4, 8, 5, 6, 7, 11, 9, 10 |
Presentation and discussion article (2) (evaluated during the session) | 3.3 % | 0 | 0 | 1, 2, 3, 4, 8, 5, 6, 7, 11, 9, 10 |
Writing (scientific paper) | 3.3 % | 0 | 0 | 1, 3, 4, 7 |
- ADAMS, H.R. Veterinary Pharmacology and Therapeutics. Iowa State University Press/Ames, 8ª Ed (2001)
- BOOTHE, D.M.. Small Animal Clinical Pharmacology and Therapeutics. 1a edició. W.B. Saunders, 2001
- BAÑOS, JE, FARRE, M. Principios de Farmacologia clínica: bases científicas de la utilización de medicamentos. Ediciones Masson, (2002).
- BRUNTON LL et al. Goodman and Gilman: Las Bases Farmacológicas de la Terapéutica. Editorial McGraw-Hill Interamericana, 11ª ed., (2006)
- BOTANA, LM. Farmacologia Veterinaria, (2016) on line:
- BRUNTON LL et al. Goodman and Gilman: Las Bases Farmacológicas de la Terapéutica. Editorial McGraw-Hill Interamericana, 11ª ed., 2006
- FLOREZ, J, ARMIJO, JA, MEDIAVILLA, A. Farmacología Humana. Barcelona: Elsevier España, 6a Ed (2014).
- GIGUÈRE S, PRESCOTT SF, BAGGOT JD, WALKER RD & DOWLING PM. Antimicrobial Therapy in Veterinary Medicina. 5th Edition (2013)
- HILAL-DANDAN, R, BRUNTON, LL. Goodman & Gilman's: Manual of Pharmacology and Therapeutics. New York: Mc-Graw-Hill Interamericana, 2nd Ed (2014).
- HITNER H, NAGLE B. Introducción a la Farmacología. Editorial Mc-Graw-Hill Interamericana, 5ª ed, (2007)
- KATZUNG B G, MASTERS SB, TREVOR AJ. Farmacología básica y clínica. Editorial McGraw-Hill Interamericana, 11a ed, 2010
- PLUMB, DC. Plumb's Veterinary Drug Handbook, 9 Ed (2018)
- RANG ANDDALE. Pharmacology, 9 Ed (2019)
- RIVIERE, JE, PAPICH, MG. Veterinary Pharmacology and Therapeutics 9 Ed (2009)
- Flashcards de Farmacologia bàsica. Com accedir-hi: entrar a la web de la biblioteca: https://www.uab.cat/biblioteques/ Desprès a revistes digitals i finalment posar: Flashcards de Farmacologia básica (hi ha tb una entrada de Flashcards de Rang&Dales)
ALTRES FONTS ONLINE
https://pubmed.ncbi.nlm.nih.gov/
World Wide Science.org
Ref seek
BASE (Bielefeld Academia Search Engine)
Medicines. The Discovery Process. Sheffield BioScience (Zeneca Pharmaceuticals). Sheffield, UK (1999).
Neuromuscular Pharmacology. Sheffield BioScience programs. 2 Woodgates Mount, North Ferriby, UK (2020).
Cardilab. Biosoft (UK and USA) info@biosoft.com www.biosoft.com (2000)