Degree | Type | Year | Semester |
---|---|---|---|
2500502 Microbiology | OT | 4 | 0 |
The responsible teacher is modified from Mercè Martí Ripoll to Roger Colobran Oriol [mailto:roger.colobran@]roger.colobran@uab.cat
To access to study "Immunology of Infectious Diseases", the student must have attained the learning skills of Immunology in the course corresponding to their degree.
SECTION I
Review of the main aspects of innate and adaptive immune response
MALT: Mucosa-Associated Lymphoid Tissue
MALT: Morphological and anatomical description. Lymphocyte recirculation
Immune response in the MALT: mechanisms of innate and adaptive immunity.
SECTION II
Immune response to bacteria
Analysis of antibacterial mechanisms mediated by innate and adaptive immunity.
Immune effector mechanisms operating against intra or extracellular bacteria.
Evasion mechanisms thatbacteria use to avoid the immune system.
Pathology and treatment of diseases caused by bacterial infections
Learning to recognize and describe diseases caused by bacterial infections that are clinically important.
Identification of emerging bacterial diseases.
Vaccines.
Seminars by specialists
SECTION III
Immune response to parasites
Learning the basics of parasitic infecccions.
Immune mechanisms used to deal with different types of parasitic infections.
Different strategies and different mechanisms used by parasites to evade the host's immune response.
Pathology and treatment of diseases caused by parasites
Learning to recognize and describe diseases caused by parasitic infections that are clinically important.
Vaccines.
Seminars by specialists
SECTION IV
Immune response to viruses
Basic concepts of antiviral immunity.
Specific mechanisms of innate and adaptive immunity involved in defense against viral infections.
Different strategies used by viruses to evade the antiviral immune response.
Pathology and treatment of diseases caused by infections
Learning to recognize and describe diseases caused by infections that are clinically important.
Identification of emerging viral diseases.
Vaccines.
Seminars by specialists
Contents of the subject*:
Section I
Review innate and adaptive immunity: inflamasoma, TLR signaling, cell lineages Th cells (Th1, Th2, Th17, regulatory T cells)...
MALT anatomy of mucosal lymphocyte recirculation, a description of cellular elements (intraepithelial lymphocytes) and humoral (IgA) and immune response associated with MALT.
Section II.
Immune response to bacteria.
Pathology of diseases caused by bacterial infections.
Seminars include a monographic session on Mycobacterium tuberculosis.
Section III.
Immune response to the parasite.
Pathology of diseases caused by parasites.
Seminars include a monographic session on Plasmodium falciparum.
Section IV.
Immune response to the virus.
Pathology of diseases caused by viral infections.
Seminars include a monographic session on HIV.
*Unless the requirements enforced by the health authorities demand a prioritization or reduction of these contents.
Teaching methodology of the subject *:
LECTURES:
The topics of the Teaching Units will be taught in 30 sessions. Some of the sessions will be taught by guest professors and specialists in the field of clinical research into diseases caused by pathogens. The content of the theory program will be taught mainly by teachers in the form of master classes with audiovisual support. The presentations used in class by the teacher will be previously available in the Virtual Campus of the subject.
SELF-LEARNING:
Autonomous learning will be based on achieving the specific learning competencies that will accompany the beginning of each Block into which the subject program is divided. It is advisable that students regularly consult the books recommended in the Bibliography section of this teaching guide to consolidate and clarify, if necessary, the contents explained in class. In this sense, it is also advisable for students to use the links indicated on the Virtual Campus, which contain videos and animations related to the processes explained in class.
COOPERATIVE LEARNING:
Problem-based learning (ABP) or CASE sessions will be scheduled. To solve the cases, the cooperative learning methodology will be applied: groups of 3 or 4 students will be made. Case information will be posted on the Virtual Campus (CV).
1) Prepare an oral presentation: choose the fundamental parts of the work and present it to the rest of the class.
2) Linked to the oral presentation, there will be an infographic accompanied by a descriptive summary of it.
The details of the work will be given during the presentation of the subject.
* Unless the restrictions imposed by the health authorities force the change in the non-contact mode. In this case, its format will be adapted to the possibilities offered by the UAB virtual tools.
Annotation: Within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.
Title | Hours | ECTS | Learning Outcomes |
---|---|---|---|
Type: Directed | |||
Classroom practicals | 12 | 0.48 | 1, 3, 2, 5, 4 |
Master classes | 30 | 1.2 | 1, 3 |
Type: Supervised | |||
Preparation of oral presentation | 17.5 | 0.7 | 1, 3, 2, 5, 4 |
Preparation of written report | 17.5 | 0.7 | 1, 3, 2, 5, 4 |
Type: Autonomous | |||
Data interpretation from an article or a problem | 20 | 0.8 | 1, 3, 2, 5, 4 |
Learning consolidation: study | 50 | 2 | 1, 3, 2, 5, 4 |
The evaluation of the course will be continued through individual tests that assess:
- Individual learning by students from exams
- Cooperative learning from the training activities scheduled as classroom practices, written and oral presentation skills.
The evaluation activities scheduled in the subject of Immunology are *:
Exams: two partial exams. Each test will be worth 35% of the final grade. Exams will be multiple choice questions of a minim of 25 questions with five options and only one correct. A correction value of 1/5 will be subtracted per every incorrect answer. To pass this part of the course, the sum of the partial exams must be more than 50% weight of the total grade. Students must achieve a minimum 40% in partial 1 to compensate with partial 2.
Cases (ABP): The cases are for cooperative work in groups of 3-4 students. They will be practical problems. The aim is for students to develop their skills of self-learning search and selection of information and eventually develop the ability to synthesize and written communication. Also workgroup.
The evaluation of cases represent 30% of the final grade in the course as follows:
i) 10% for the writtenwork.
ii) 20% oral presentation.
To pass this part of the course grades must be greater than 50% of their total value.
The final grade for the course will be composed of the score of the two partial exams and cases.
Along the semester, there will be questionnaires online or in class that will serve as continuous evaluation and can help the final scores.
If they fail to pass the course or want to improve grades, students can retake a full or partial final exam. By doing an exam to improve grades, the student renounces to the previous score obtained.
Failure to appear to any of the tests must be justifiedto get a second chance.
To be eligible for the retake process, the student should have been previously evaluated in a set of activities equaling at least two thirds of the final score of the course. Thus, the student will be graded as Non-evaluable if the weighing of all conducted evaluation activities is less than 67% of the final score.
*Student’s assessment will performed face-to-face, unless the requirements enforced by the health authorities demand shifting to the online modality. In this case, the format will be adapted (maintaining its weighting in the final grade) to the possibilities offered by the UAB’s virtual tools.
Title | Weighting | Hours | ECTS | Learning Outcomes |
---|---|---|---|---|
Oral presentation of team work | 20% | 0 | 0 | 1, 3, 2, 5, 4 |
Partial Examination 1 | 35% | 1.5 | 0.06 | 1, 3, 2 |
Partial Examination 2 | 35% | 1.5 | 0.06 | 1, 3, 2 |
Written Report | 10% | 0 | 0 | 2, 5, 4 |
Primer to the Immune Response, 2nd Edition, by Tak W. Mak, Mary Saunders and Bradley Jett. 2n Edition, ELSEVIER (2014). ISBN: 9780123852458
Review of Medical Microbiology and Immunology by W. Levinson, P. Chin-Hong, E.A. Joyce, J. Nussbaum, B. Schwartz. McGraw-Hill, 16th edition, (2020). ISBN-13: 978-1260116717.
Deja Review Microbiology and Immunology. E. Chen, S. Kasturi. McGraw-Hill Ed. 2nd ed (2010). ISBN-13: 978-0071627153.
Elsevier's Integrated Review Immunology and Microbiology: With STUDENT CONSULT Online Access, by Jeffrey K. Actor - Elsevier Science Health Science Division (2012). ISBN: 978-0323074476.
BRS Microbiology and Immunology, by Arthur G. Johnson, Richard J. Ziegler, Louise Hawley. Lippincott Williams & Wilkins 5th (2009). ISBN: 9780781789127.
Janeway's Immunobiology by K. Murphy, C. Weaver. Ltd/Garland Science, NY & London, 9th ed (2016). ISBN: 9780815345053.
Kuby Immunology (with web support) by J. Punt, S. Stranford, P Jones and J. Owen.W.H. Freeman and Co. Ltd, 8th ed (2018). ISBN13: 9781319114701
Cellular and Molecular Immunology by Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai, Saunders, 10th ed (2021). ISBN13: 978-0323757485.
Roitt's Essential Immunology, by Peter Delves, Seamus Martin, Dennis Burton, Ivan Roitt, Wiley-Blackwell Ed., 13th ed (2017). ISBN 9781118415771.
Principles of Mucosal Immunology (Society for Mucosal Immunology), by Phillip D. Smith, Thomas T. McDonald, Richard S. Blumberg Ed. Garland Science 2nd ed. (2020).
.Mim's Pathogenesis of Infectious disease. A.A; Nash, R.G. Dalziel & J. R. Fitzgerald. Academic Press Ed. 6th Edition. (2015). EBook ISBN: 978012397781; Paperback ISBN: 9780123971883
Principles of Molecular Virology.A.J Cann. Academic Press Ed. 6th Edition. (2016). EBook ISBN: 9780128019559; Paperback ISBN: 9780128019467.
Unifying Michobial Mechanisms. M. F. Cole. Garland Science 1st ed. (2029). eBook ISBN: 9780429262777.
Advances in Immunology
http://www.elsevier.com/wps/find/bookdescription.cws_home/716912/description#description
http://www.sciencedirect.com/science/bookseries/00652776
Annual Review of Immunology
http://arjournals.annualreviews.org/loi/immunol
Current Opinion in Immunology
http://www.elsevier.com/wps/find/journaldescription.cws_home/601305/description#description
http://www.sciencedirect.com/science/journal/09527915
Immunological Reviews
http://www3.interscience.wiley.com/journal/118503650/home
Nature Reviews in Immunology
http://www.nature.com/nri/index.html
Seminars in Immunology
http://www.elsevier.com/wps/find/journaldescription.cws_home/622945/description#description
Trends in Immunology
http://www.cell.com/trends/immunology/
Microbiology and Immunology
http://onlinelibrary.wiley.com/journal/10.1111/%28ISSN%291348-0421
Journal of Microbiology, Immunology and Infection
http://www.e-jmii.com/
Comparative Immunology, Microbiology and Infectious Diseases
http://www.elsevier.com/wps/find/journaldescription.cws_home/496/description#description
Microsoft Office is sufficient to carry out this subject.