Degree | Type | Year | Semester |
---|---|---|---|
4313772 Advanced Biotechnology | OT | 0 | 1 |
To follow the module it is necessary to have a basic formation in Biochemical Engineering, in fundamental aspects of Bioprocess Engineering, in Bioreactors and some very basic concepts of recombinant DNA and Genetic Engineering.
The objective of this module is to familiarize the student with the most important tools used in a bioprocess, and its application in the design and operation of bioprocesses in their future professional careers. In order to achieve this objective, different cellular factories will be explored, designed, integrated and optimized for producing industrial biotechnological products, integrating the production and purification of the bioproduct in a reproducible way (BIOPAT concept) and economically viable Bioprocess Engineering. The quality and safety regulations of bioproducts from different fields will also be explained and the principles on which the scale up of a bioprocess is based will be presented.
1.- Introduction to the industrial production of bioproducts. Scale up in bioreactors
2.- Bioprocess design based on quality.
2.1.- Quality by Design (QbD) / Process Analytical Technology (PAT)
2.2.-Good Manufacturing Practice (GMPs). Good Laboratory Practices (BPLs),
3.-Cell factories: Animal cell culture
4.-Cell factories: Pichia pastoris.
5.-Cell factories: Escherichia coli.
6.- Laboratory work at Fermentation Pilot Plant
Lectures on the topics of the syllabus.
Seminars on aspects of the industrial world of Biotechnology by experts invited from the sector.
Elaboration of gruop works. Group activity. Students will prepare a report on a topic related to the contents, at the teacher's proposal. These works will be exposed and defended in public.
Laboratory work. The students will carry out practices in the pilot plant of fermentation, consisting of the follow-up of a process of production of a recombinant protein.
Title | Hours | ECTS | Learning Outcomes |
---|---|---|---|
Type: Directed | |||
Experimental work | 20 | 0.8 | 16, 6, 7, 12, 15, 1, 14, 13, 17, 18 |
Lectures | 33.5 | 1.34 | 16, 2, 4, 5, 3, 6, 7, 8, 10, 11, 9, 12, 15, 1, 14, 13, 17, 18 |
seminars | 4 | 0.16 | 16, 12, 15, 1, 17 |
Type: Supervised | |||
Laboratori reports | 15 | 0.6 | 16, 2, 4, 5, 3, 9, 1, 14, 17, 19 |
group work | 35 | 1.4 | 16, 3, 10, 11, 9, 14, 13, 17, 19, 18 |
Type: Autonomous | |||
Lab work preparation | 10 | 0.4 | 2, 4, 5, 6, 12, 15, 1, 14, 13, 17, 18 |
Search of documentation and bibliography | 28 | 1.12 | 16, 12, 15, 17, 19, 18 |
Study | 50 | 2 | 16, 2, 4, 5, 3, 6, 7, 8, 10, 11, 9, 12, 15, 1, 14, 13, 17, 18 |
writing work and oral exposure | 24.5 | 0.98 | 16, 12, 15, 1, 14, 17, 19, 18 |
Evaluation of the theoretical part of the module:
Continuous assessment
Individual written evaluation: It is 70% of the final grade. Four partial tests corresponding to different subjects of the course are carried out with a weight of 25% each of them. If in the individual written evaluation the student obtained a grade lower than 3/10, he will not pass the module.
Evaluation of the defense and oral presentation of a research paper (30%)
Final evaluation:
Students who do not pass the continuous assessment will have a global test of written individual final recovery. Whenever this test is exceeded with a grade higher than 3/10, it will be done with the grade of the oral presentation.
Global evaluation of the module
Evaluation of laboratory practices in a fermentation pilot plant (25%).
Evaluation of the theoretical part of the module (75%). Minimum note of this part to approve trhe module 3.5/10
See more details in spanish version
Title | Weighting | Hours | ECTS | Learning Outcomes |
---|---|---|---|---|
4 Writing exams | 13,1% each | 3 | 0.12 | 16, 2, 4, 5, 3, 6, 7, 8, 10, 11, 9, 12, 15, 1, 14, 13, 17, 18 |
Assesment of Lab work | 25 | 1 | 0.04 | 16, 2, 4, 5, 3, 11, 12, 15, 1, 14, 13, 17, 19 |
Assessment of oral presentation | 22,5% | 1 | 0.04 | 16, 12, 15, 1, 17, 19, 18 |
The bibliography needed to follow the module can be consulted through the virtual platform. In parallel, the student will have to carry out searches and specific bibliographical consultations for the elaboration of their group work.