Histology and General Physiology
Code: 101894 ECTS Credits: 6| Degree | Type | Year | Semester |
|---|---|---|---|
| 2501230 Biomedical Sciences | OB | 1 | 2 |
Contact
- Name:
- Ruben Lopez Vales
- Email:
- Ruben.Lopez@uab.cat
Use of Languages
- Principal working language:
- catalan (cat)
- Some groups entirely in English:
- No
- Some groups entirely in Catalan:
- No
- Some groups entirely in Spanish:
- No
Teachers
- Ignasi Roig Navarro
Prerequisites
No official prerequisites are defined for this subject. However, it is recommended that the student has acquired the basic knowledge and competences of the subjects corresponding to Cell Biology, Biochemistry and Molecular Biology, and Biophysics.
Objectives and Contextualisation
The subject Histology and General physiology is programmed during the second semester of the first course of the Degree of Biomedical Sciences and develops the knowledge of the basic principles of the function of cells and tissues of the human organism. The acquisition of the competences of this subject will allow the student to be well prepared to confront the study of the histology physiology of the different systems of the human body during the second course.
The general training objectives of the course are:
- Differentiate different types of tissues by their histological and functional characteristics.
- Identify the different cell types that constitute each tissue and describe its most important differential characteristics.
- To learn the basic mechanisms of body tissue operation.
- Use textbooks, atlases and specific Internet resources for the study of matter.
- Develop with ease in the management of the optical microscope and the study of histological preparations.
- To learn the electrophysiological techniques for evaluating the nervous and muscular system.
Unless the restrictions imposed by the health authorities require a prioritization or reduction of such content.
Competences
- Act with ethical responsibility and respect for fundamental rights and duties, diversity and democratic values.
- Make changes to methods and processes in the area of knowledge in order to provide innovative responses to society's needs and demands.
- Students must be capable of applying their knowledge to their work or vocation in a professional way and they should have building arguments and problem resolution skills within their area of study.
- Students must be capable of collecting and interpreting relevant data (usually within their area of study) in order to make statements that reflect social, scientific or ethical relevant issues.
- Students must be capable of communicating information, ideas, problems and solutions to both specialised and non-specialised audiences.
- Students must develop the necessary learning skills to undertake further training with a high degree of autonomy.
- Students must have and understand knowledge of an area of study built on the basis of general secondary education, and while it relies on some advanced textbooks it also includes some aspects coming from the forefront of its field of study.
- Take account of social, economic and environmental impacts when operating within one's own area of knowledge.
- Work as part of a group with members of other professions, understanding their viewpoint and establishing a constructive collaboration.
Learning Outcomes
- Act with ethical responsibility and respect for fundamental rights and duties, diversity and democratic values.
- Make changes to methods and processes in the area of knowledge in order to provide innovative responses to society's needs and demands.
- Students must be capable of applying their knowledge to their work or vocation in a professional way and they should have building arguments and problem resolution skills within their area of study.
- Students must be capable of collecting and interpreting relevant data (usually within their area of study) in order to make statements that reflect social, scientific or ethical relevant issues.
- Students must be capable of communicating information, ideas, problems and solutions to both specialised and non-specialised audiences.
- Students must develop the necessary learning skills to undertake further training with a high degree of autonomy.
- Students must have and understand knowledge of an area of study built on the basis of general secondary education, and while it relies on some advanced textbooks it also includes some aspects coming from the forefront of its field of study.
- Take account of social, economic and environmental impacts when operating within one's own area of knowledge.
- Work as part of a group with members of other professions, understanding their viewpoint and establishing a constructive collaboration.
Content
GENERAL HISTOLOGY
TISSUE CONCEPT
Cellular and extracellular components.
–Classification of animal tissues.
EPITHELIAL TISSUE
- Lining epithelia
-Glandular epithelium.
CONJUNCTIVE TISSUE
-Extracellular matrix.
-Fibroblasts and free cells.
-Varieties of connective tissue.
ADIPOSE TISSUE
-The adipocytes.
-Unicellular and multilocular adipose tissue.
CARTILAGINOUS TISSUE
-Cartilaginous matrix.
-Chondrocytes.
-Varieties of cartilage tissue.
BONE TISSUE
-Architectural organization of the bone.
-Bone matrix.
-Osteoblast-Osteophyte. Osteoclast.
-Varieties of bone tissue.
BLOOD
-Blood plasm and elements of forms.
MUSCLE TISSUE
-Varieties of muscle tissue.
-Striated muscle fiber.
-Cardiac muscle fiber.
-Smooth muscle fiber.
NERVOUS TISSUE
-Neuron. Axonal transport
-Neuroglia.
GENERAL PHYSIOLOGY
INTRODUCTION
-Basics of cell physiology
-Function of cellular compartments
IONIC TRANSPORT THROUGH THE CELL MEMBRANE Cell
-Concentrations in intracellular and extracellular medium ions
-Diffusion through the cell membrane. Ionic channels
PHYSIOLOGY OF CELLS EPITHELIAL CELLS
-Functional structure of the epithelium
-Epithelial Transport
-Physiology of the epithelial glands. Secretion mechanisms
ELECTRICAL CELLULAR PHENOMENA CELLULAR
-Transmembrane resting potential
-Local potential and excitability
-Action potential.Spread of action potential
SYNAPTIC TRANSMISSION
-Electric synapses.
-Chemical synapses. Synapses structure and function
-General characteristics of the chemical neurotransmission
-Postsynaptic Receptors.Postsynaptic potentials
MUSCLE EXCITATION AND CONTRACTION
-Functional organization of striated muscle fibers
-Electrical phenomena
-Mechanical phenomena
-Variations in muscle contractility
-Energetic muscle contraction
-Types of skeletal muscle fibers
-Contraction of smooth muscle fibers
-Contraction of skeletal muscle
AXONAL REGENERATION AFTER INJURIES TO THE NERVOUS SYSTEM
- Walleriana Degeneration
- Axonal regeneration in peripheral nervous system injuries
- Axonal regeneration in lesions of the central nervous system
Methodology
Lectures:
Systematic explanation of the subject topics, giving relevance to the most important concepts. The student acquires the basic scientific knowledge of the subject in theory classes, which will be complement by self study of the themes of the subject program
Seminar Sessions:
Presentation and work on cases or problems of relevance for the learning of the subject. The knowledge acquired in the theory classes and in the personal study are applied to the resolution of practical cases that are posed in the seminars. Students work in small groups.
Tutorials
The tutorials will be done in a personalized way to the teacher's office (hours to be agreed). The tutorías aim to clarify concepts, to establish the acquired knowledge and to facilitate the study by the students. They can also be used to resolve doubts that students have about preparing the seminars.
THE TEACHING METHODOLOGY PROPOSED HEREIN MAY POTENTIALL UNDERGO SOME MODIFICATIONS ACCORDING TO THE RESTRICCIONS IMPOSED BY THE HEALTH AUTHORITIES
Activities
| Title | Hours | ECTS | Learning Outcomes |
|---|---|---|---|
| Type: Directed | |||
| Lectures | 36 | 1.44 | |
| Seminars | 10 | 0.4 | |
| Type: Supervised | |||
| Individual tutorials | 4 | 0.16 | 9 |
| Type: Autonomous | |||
| Resolution of problems | 10 | 0.4 | 9 |
| Study | 70 | 2.8 | |
| Work Elaboration | 10 | 0.4 | 9 |
Assessment
Module: General Histology
The evaluation system is organized into two sections, which evaluated individually and has a specific weight in the final grade of the module:
•Written test (80% of the final mark).
It is imperative to have at least 5 points out of 10 in each of the parts
•Seminars (20% of the final note).
Attendance at seminars is mandatory. Absence from seminars without justification is penalized.
Module: General Physiology
The evaluation system is organized into two sections, which evaluated individually and has a specific weight in the final grade of the module:
•Examination of objective tests of multiple and/or written responses
(80% of the final mark). Students who obtain a qualification lower than 5 (out of 10) in this test will not be able to weigh it with the grade obtained in the presentation of problems and cases and, therefore, they will have perform the final maturity exam.
•Evaluation of the preparation and presentation of the problems and cases (activity evaluated via Moodle) (20% of the final mark)
Partial assessments will be made of the two modules of the course. In the case of failing a module of the subject, a final maturity test will be carried out of those failed modules.
It is necessary to obtain a qualification ≥5 in the two modules to pass the subject.
Repeaters will only be evaluated from the specific modules that did not pass.
This exemption will be maintained for a period of three enrolments.
Assessment Activities
| Title | Weighting | Hours | ECTS | Learning Outcomes |
|---|---|---|---|---|
| Preparation and presentation of the problems and cases (Histology) | 10 | 1 | 0.04 | 7, 6, 5, 3, 4, 9 |
| Preparation and presentation of the problems and cases (Physiology) | 10 | 3 | 0.12 | 7, 6, 5, 3, 4, 9 |
| Theory exam (Histology) | 40 | 4 | 0.16 | 1, 8, 2, 7, 6, 5, 3, 4, 9 |
| Theory exam (Physiology) | 40 | 2 | 0.08 | 1, 8, 2, 7, 6, 5, 3, 4, 9 |
Bibliography
- BERNE R, LEVY M. Physiology (7th Ed.). Elsevier-Mosby, 2018.
- GARTNER, L.P. HIATT, J.L. Texto Atlas de Histologia. Mc Graw-Hill, 2015.
- GENESER, F.: Histology (ed. Panamericana) 2014.
- GUYTON AC, HALL JE. Treaty of Medical Physiology (13th ed.). Elsevier-Saunders, 2016.
- KIERSZENBAUM, A L. Histology and Cell Biology. Introduction to Pathological Anatomy. Elsevier-Mosby 2012.
- ROSS AND PAWLINA, Histology (6aed.) PanAmerican, 2012.
- MATTHEWS GG. Neurobiology. Molecules, Cells, and Systems. (2ª ed.). Blackwell Science, 2001.
- OVALLE. Netter's Essential Histology. Saunders, 2008
- PURVES D. Neuroscience (5th ed.). Pan American, 2016 (Digital accés from UAB)
- STEVENS, A. Y LOWE, J.: Histología humana (ed. Elsevier) 1995.
- THREE JAF. Human Physiology (4th ed.). Mc Graw Hill-Interamericana, 2010.
- VANDER A, SHERMAN J, LUCIANO D. Human Physiology. The mechanism of the body (14th Ed). Mc Graw Hill- Interamericana, 2016 WELSCH. U. Sobotta Histologia (2ª ed.). Panamericana, 2008.ç- BERNE R, LEVY M. Fisiología (6ª ed.). Elsevier-Mosby, 2009.